References of "Marty, M"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailReduction of the Serum Levels of a Specific Biomarker of Cartilage Degradation (Coll2-1) by Hyaluronic Acid (KARTILAGE® CROSS) Compared to Placebo in Painful Knee Osteoarthritis Patients: The EPIKART Study, a Pilot Prospective Comparative Randomized Double Blind Trial
Henrotin, Yves ULiege; Berenbaum, F.; Chevalier, X. et al

in BMC Musculoskeletal Disorders (2017), 18(1),

Background: Viscosupplementation is a symptomatic treatment of the knee osteoarthritis based on the intra-articular injection of hyaluronic acid (IAHA). Although many studies have investigated its effect ... [more ▼]

Background: Viscosupplementation is a symptomatic treatment of the knee osteoarthritis based on the intra-articular injection of hyaluronic acid (IAHA). Although many studies have investigated its effect on symptoms, few clinical studies have focused on its effects on biologicals markers of cartilage metabolism. In this study, we assessed the effect of an intra-articular injection of a reticulated hyaluronic acid compound on the level of a specific biomarker of type II collagen degradation. Methods: Eighty one patients with symptomatic knee osteoarthritis were included in this randomized placebo controlled trial testing a reticulated hyaluronic acid (HA) with mannitol (KARTILAGE® CROSS, 16 mg/ml, one single injection of 2.2 mL; IAHA) versus saline solution. Primary outcome was the percentage of patients with a reduction of at least 10 nmol/l of serum Coll2-1 between baseline and day 90 (D90, 3 months after injection). Secondary outcomes concerned clinical evaluation and tolerance to the study product. Results: A significant effect of IAHA was revealed by the sensitivity analysis of the decrease in cartilage marker. In the intention-to-treat population, the percentage of patients showing a decrease in the levels of serum Coll2-1 between inclusion and D90 showed was higher in HA (56.8%) than in placebo group (28.6%; P = 0.01). The same significant difference was observed between groups in the per protocol population (57.1% vs 29.0%; P = 0.02) corresponding to all patients having received the intra-articular injection (IA), being evaluated for the primary outcome on D-10 and D90, and with no major defined deviation. No significant differences between groups were observed on the changes in function (Lequesne index) or pain and on the number of adverse events. Conclusions: This is the first randomized double-blind placebo controlled trial showing that IA injection of reticulated HA with mannitol in knee osteoarthritis patients can reduce the serum levels of Coll2-1, a marker specific of type II collagen degradation. This finding suggests that IAHA may have a beneficial effect on cartilage degradation and that Coll2-1 could be used for the assessment of a single intra-articular treatment in clinical trials. Trial registration: NCT02951585; clinicaltrial.gov. Retrospectively registered on October 28, 2016. © 2017 The Author(s). [less ▲]

Detailed reference viewed: 11 (0 ULiège)
Full Text
Peer Reviewed
See detailHow much does the Dallas Pain Questionnaire score have to improve to indicate that patients with chronic low back pain feel better or well?
Marty, M; Courvoisier, D; Foltz, V et al

in European Spine Journal (2016), 25

Purpose: The Dallas Pain Questionnaire (DPQ) assesses the impact of low back pain (LBP) on four components (0–100) of daily life. We estimated the minimal clinically important improvement (MCII) and the ... [more ▼]

Purpose: The Dallas Pain Questionnaire (DPQ) assesses the impact of low back pain (LBP) on four components (0–100) of daily life. We estimated the minimal clinically important improvement (MCII) and the patient acceptable symptom state (PASS) values of DPQ in LBP patients. Methods: 142 patients with LBP lasting for at least 4 weeks completed a battery of questionnaires at baseline and 6 months later. Questions for MCII addressed patientreported response to treatment at 6 months on a five-point Likert scale, while a yes/no question concerning satisfaction with present state was used to determine PASS. MCII wascomputed as the difference in mean DPQ scores between patients reporting treatment as effective vs. patients reporting treatment as not effective, and PASS was computed as the third quartile of the DPQ score among patients who reported being satisfied with their present state. Results: MCII values were 22, 23, 2 and 10 for daily activities, work and leisure, social interest, and anxiety/depression, respectively. PASS values were 29, 23, 20 and 21 for the four components, respectively. The PASS total score threshold of 24 correctly classified 84.1 % of the patients who reported being unsatisfied with their present state, and 74.7 % of patients reported being satisfied. Conclusions: These values give information of paramount importance for clinicians in interpreting change in DPQ values over time. Authors should be encouraged to report the percentage of patients who reach MCII and PASS values in randomized clinical trials and cohort studies to help clinicians to interpret clinical results. [less ▲]

Detailed reference viewed: 26 (3 ULiège)
Full Text
Peer Reviewed
See detailCore Outcome Measure Index for low back patients: do we miss anxiety and depression?
Cedraschi, C; Marty, M; Courvoisier, DS et al

in European Spine Journal (2016), 25

Detailed reference viewed: 10 (2 ULiège)
Full Text
Peer Reviewed
See detailPrise en charge des patients lombalgiques : les mots du thérapeute aussi importants que ses mains
Demoulin, Christophe ULiege; Roussel, Nathalie; Marty, M. et al

in Axxon Exclusif (2015)

Detailed reference viewed: 61 (12 ULiège)
Full Text
Peer Reviewed
See detailHyaluronan for knee osteoarthritis: an updated meta-analysis of trials with low risk of bias
Richette, P.; Chevalier, X.; Ea, H. K. et al

in RMD Open (2015), 1(1), 000071

BACKGROUND: The effectiveness of intra-articular hyaluronic acid (IAHA) injection for knee osteoarthritis (KOA) is debated. OBJECTIVES: To evaluate the effect of IAHA for patients with KOA by analysing ... [more ▼]

BACKGROUND: The effectiveness of intra-articular hyaluronic acid (IAHA) injection for knee osteoarthritis (KOA) is debated. OBJECTIVES: To evaluate the effect of IAHA for patients with KOA by analysing data from trials of IAHA versus placebo with low risk of bias, to provide the highest level of evidence. METHODS: A systematic review and meta-analysis was conducted. Randomised controlled trials (RCTs) with a low risk of bias (adequate randomisation and concealment and double-blind design) that investigated IAHA versus placebo (saline solution) injection were eligible. The primary efficacy measure was pain intensity and secondary outcome function at 3 months. The treatment effect was summarised with the standardised mean difference (SMD) calculated from differences in means of pain and function measures between treatment and control groups at 3 months. Trials were pooled by a random-effects model with DerSimonian and Laird weights. Statistical heterogeneity was explored by a visual exploration of forest plots and the I(2) statistic. RESULTS: A total of eight RCTs (2 199 randomised patients) met our inclusion criteria. IAHA significantly reduced the pain intensity (SMD=-0.21, 95% CI (95% CI) -0.32 to -0.10) and improved function (SMD=-0.12, 95% CI -0.22 to -0.02). Trials showed no heterogeneity. CONCLUSIONS: This meta-analysis of high-quality trials of IAHA versus placebo shows that IAHA provides a moderate but real benefit for patients with KOA. [less ▲]

Detailed reference viewed: 8 (0 ULiège)
Full Text
Peer Reviewed
See detailPropriétés métrologiques du Dallas Pain Questionnaire
Marty, M; Genevay, S; Courvoisier, D et al

in Revue du Rhumatisme (2014, December), 81S

Detailed reference viewed: 38 (3 ULiège)
Full Text
Peer Reviewed
See detailDegré de satisfaction d’une population asymtomatique et symtomatique à l’égard d’une brochure originale sur la lombalgie
Demoulin, Christophe ULiege; Haugustaine, Linda; GROSDENT, Stéphanie ULiege et al

in Revue du Rhumatisme (2014, December), 81S

Detailed reference viewed: 78 (21 ULiège)
Peer Reviewed
See detailAre the back educational interventions effective for preventing low back pain
Demoulin, Christophe ULiege; Marty, M.; Genevay, S. et al

in Abstract book of the 8th Interdisciplinary World Congress on Low Back and Pelvic Pain (2013, October)

Detailed reference viewed: 18 (2 ULiège)
Full Text
See detailAnalyse de l'efficacité des programmes d'éducation rachidienne pour la prévention des lombalgies
Demoulin, Christophe ULiege; Marty, M.; Genevay, S. et al

in Neurone (2013), 18

Detailed reference viewed: 47 (6 ULiège)
Full Text
Peer Reviewed
See detailEffectiveness of preventive back educational interventions for low back pain: a critical review of randomized controlled clinical trials
Demoulin, Christophe ULiege; Marty, M.; Genevay, S. et al

in European Spine Journal (2012), 21

Detailed reference viewed: 17 (1 ULiège)
Full Text
Peer Reviewed
See detailLa volition est-elle un chaînon manquant de la prise en charge du patient lombalgique ?
Broonen, Jean-Paul ULiege; Marty, M.; Legout, V. et al

in Revue du Rhumatisme (2011), 78(1), 238-41

Patients with nonspecific chronic low back pain are typically prescribed a regimen of regular physical exercises to improve pain and function, increase workability, and prevent pain recurrence. However ... [more ▼]

Patients with nonspecific chronic low back pain are typically prescribed a regimen of regular physical exercises to improve pain and function, increase workability, and prevent pain recurrence. However, adherence to home exercise programs is often partial at best. Patients often fail to translate their intention to exercise (motivation) into action (implementation). Volition is the mental activity by which intentions are implemented. In this review, we argue that volition may be crucial to the successful rehabilitation of patients with low back pain. Obstacles to the implementation of intentions are described, as well as factors that promote implementation, most notably the conscious formation of implementation intentions. [less ▲]

Detailed reference viewed: 67 (11 ULiège)
Full Text
Peer Reviewed
See detailInformation delivery to patients with acute low back pain: a longitudinal observational randomized survey
Marty, M; Moyse, D; Bazin, T et al

in Annals of the Rheumatic Diseases (2009), 68(Suppl 3), 700

Detailed reference viewed: 16 (1 ULiège)
Full Text
Peer Reviewed
See detailInformation des patients souffrant de lombalgie aigue: enquête sur les pratiques des médecins français
Marty, M; Moyse, D; Bazin, T et al

in Revue du Rhumatisme (2008), 75

Detailed reference viewed: 8 (0 ULiège)
Full Text
Peer Reviewed
See detailL'information basée sur un modèle biopsychosocial modifie positivement les croyances des adolescents
Henrotin, Yves ULiege; Henot, B; Parmentier, I et al

in Revue du Rhumatisme (2008), 75

Detailed reference viewed: 9 (0 ULiège)
Full Text
See detailL'information du patient lombalgique.
Marty, M.; Henrotin, Yves ULiege

in Rhumatologie Pratique (2007), 242

Detailed reference viewed: 25 (8 ULiège)