References of "Maquet, Pierre"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailProposal of a new tDCS safety screening tool TSST (Transcranial direct current stimulation Safety Screening Tool)
Bornheim, Stephen ULiege; Croisier, Jean-Louis ULiege; Maquet, Pierre ULiege et al

in American Journal of Physical Medicine and Rehabilitation (in press)

Detailed reference viewed: 60 (17 ULiège)
Full Text
Peer Reviewed
See detailSuccessful treatment of hand dystonia with Botulinum Toxin in a DYT12 patient
DEPIERREUX, Frédérique ULiege; PARMENTIER, Eric ULiege; HARDY, Pierre-Yves et al

Poster (2019, May 11)

We present the case of a young boy suffering from DYT12 (Rapid-onset dystonia-parkinsonism), presenting with generalized dystonia. Left hand dystonia has been treated successfully with botulinum toxin ... [more ▼]

We present the case of a young boy suffering from DYT12 (Rapid-onset dystonia-parkinsonism), presenting with generalized dystonia. Left hand dystonia has been treated successfully with botulinum toxin, under double guidance techniques (EMG and ultrasound) [less ▲]

Detailed reference viewed: 18 (1 ULiège)
Full Text
Peer Reviewed
See detailLa tDCS en phase aiguë d’un AVC : un outil rééducatif
Bornheim, Stephen ULiege; Croisier, Jean-Louis ULiege; Elkebir, Kamel Eddine ULiege et al

in Kinesitherapie, La Revue (2019, February), 19(206), 83

Detailed reference viewed: 32 (5 ULiège)
Full Text
Peer Reviewed
See detailCortical reactivations during sleep spindles following declarative learning
Jegou, A.; Schabus, M.; Gosseries, Olivia ULiege et al

in NeuroImage (2019), 195

Increasing evidence suggests that sleep spindles are involved in memory consolidation, but few studies have investigated the effects of learning on brain responses associated with spindles in humans. Here ... [more ▼]

Increasing evidence suggests that sleep spindles are involved in memory consolidation, but few studies have investigated the effects of learning on brain responses associated with spindles in humans. Here we used simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) during sleep to assess haemodynamic brain responses related to spindles after learning. Twenty young healthy participants were scanned with EEG/fMRI during (i) a declarative memory face sequence learning task, (ii) subsequent sleep, and (iii) recall after sleep (learning night). As a control condition an identical EEG/fMRI scanning protocol was performed after participants over-learned the face sequence task to complete mastery (control night). Results demonstrated increased responses in the fusiform gyrus both during encoding before sleep and during successful recall after sleep, in the learning night compared to the control night. During sleep, a larger response in the fusiform gyrus was observed in the presence of fast spindles during the learning as compared to the control night. Our findings support a cortical reactivation during fast spindles of brain regions previously involved in declarative learning and subsequently activated during memory recall, thereby promoting the cortical consolidation of memory traces. © 2019 Elsevier Inc. [less ▲]

Detailed reference viewed: 19 (0 ULiège)
Peer Reviewed
See detailSleep fragmentation is associated with brain tau but not amyloid-β burden in healthy older adults
Chylinski, Daphné ULiege; Rudzik, Franziska; Coppieters't Wallant, Dorothe ULiege et al

Conference (2018, November 09)

Detailed reference viewed: 28 (7 ULiège)
Full Text
Peer Reviewed
See detailNMOSD with anti-MOG antibodies following anti-TNFα therapy: A case report
LOMMERS, Emilie ULiege; DEPIERREUX, Frédérique ULiege; HANSEN, Isabelle ULiege et al

in Multiple Sclerosis and Related Disorders (2018), 26

Tumor necrosis factor α (TNFα) inhibitors are highly effective and a therapeutic choice for several inflammatory diseases. Their broad and long-term use is associated with a growing number of paradoxical ... [more ▼]

Tumor necrosis factor α (TNFα) inhibitors are highly effective and a therapeutic choice for several inflammatory diseases. Their broad and long-term use is associated with a growing number of paradoxical autoimmune events including demyelinating lesions of the central nervous system (CNS). We report and discuss a case of neuromyelitis optica spectrum disorder (NMOSD) with positive myelin oligodendrocyte glycoprotein antibodies (MOG-IgG1) following anti-TNFα therapy for a pustular psoriasis. [less ▲]

Detailed reference viewed: 45 (8 ULiège)
Peer Reviewed
See detailArousals during sleep are associated with brain tau burden in healthy older individuals
Chylinski, Daphné ULiege; Rudzik, Franziska; Coppieters't Wallant, Dorothe ULiege et al

Poster (2018, October 19)

Detailed reference viewed: 23 (7 ULiège)
Peer Reviewed
See detailMRI Multiparameter measures as relevant explanatory variables of cognitive but not physical fatigue in Multiple Sclerosis
Guillemin, Camille ULiege; LOMMERS, Emilie ULiege; DELRUE, Gaël ULiege et al

Poster (2018, October 13)

Introduction: Fatigue symptoms are highly frequent in patients with multiple sclerosis (MS). However, the underlying brain and clinical mechanisms associated specifically to feeling of cognitive and ... [more ▼]

Introduction: Fatigue symptoms are highly frequent in patients with multiple sclerosis (MS). However, the underlying brain and clinical mechanisms associated specifically to feeling of cognitive and physical fatigue remain largely misunderstood. Aim of study: To investigate whether subjective cognitive and physical fatigue depend on different sets of brain and clinical variables in MS. Methods: Multiparameter mapping (MPM) MRI data (R1 parameter in central grey matter (GM), R2 in cortical and central GM, R2 in cortical white matter (WM), PD in central GM and in cortical WM), and clinical data (age, depression, anxiety, cognitive and physical fatigue scores at the M-FIS; disease duration and EDSS score for patients) were collected among MS patients (n=35) and healthy controls (n=28). Stepwise regression analysis for the cognitive and physical sub-scores of the M-FIS were performed in each group, using clinical and MRI variables. Results: Variance of cognitive M-FIS score for patients was explained with a model taking into account anxiety, depression and measures of cortical and central grey matter (R² = 0.5397, p < .0001). For controls, the model included age, depression and R2 parameter in cortical white matter (R²=0.4137, p = 0.0045). The model with physical M-FIS score included EDSS and anxiety for patients (R² = 0.3834, p = 0.0004), but age and depression for controls (R²= 0.4908, p = 0.0002). Conclusions: These results suggest (1) that the determinants of subjective fatigue vary between MS and control participants; (2) that only cognitive fatigue is linked to brain characteristics. These results stress the need to study cognitive and physical fatigue as two separate entities in MS. [less ▲]

Detailed reference viewed: 84 (6 ULiège)
Full Text
Peer Reviewed
See detailNew spectral analysis method to identify trait-like features in NREM sleep power spectra
Hammad, Grégory ULiege; Muto, Vincenzo ULiege; Gaggioni, Giulia ULiege et al

Conference (2018, September 26)

Introduction: Variability among individuals in sleep/wake biology and behaviour is pervasive. Sleep/wake-related variability involves individual trait-like features (ITLF). In order to study ITLF, we ... [more ▼]

Introduction: Variability among individuals in sleep/wake biology and behaviour is pervasive. Sleep/wake-related variability involves individual trait-like features (ITLF). In order to study ITLF, we developed an advanced spectral analysis method (ASAM) to compare in a systematic and reproducible way 3 features of NREM power spectra (PS). As sleep spindles (SS) have been reported several times to be an important ITLF, we focused on a broad range of sigma activity (10 − 18Hz). Methods: The ASAM is composed of three main steps. First, EEG sleep recording is preprocessed and the NREM PS is computed for each channel of interest. Second, three characteristic features from the NREM PS related to sigma peak activity are extracted: magnitude, peak location and standard deviation. Third, the intra-individual stability and the inter-individual variability of these features, as well as the influence of sleep perturbations, are statistically tested using the Intra-Class Correlation (ICC) coefficient and the Wald Z-test. The performance of the ASAM was assessed using different polysomnography-derived sleep recordings from 16 healthy young male subjects (18-30 years). For each subject, these recordings were acquired in 5 different “sleep contexts”: the acquisition was varied from 4h to 12h and was performed at different circadian phases. Results: All three features of sigma activity (magnitude, peak location and its standard deviation) were recognized as important ITLFs (ICC = 0.74, 0.94 and 0.63 respectively). Furthermore, the inter-individual variability of these three features was significant different from zero (Wald Z-test ps < 0.05). Conclusion: Three aspects of NREM PS sigma activity are recognized as important ITLFs. It is also showed that even though these features changed according to sleep context, they remained specific to the individuals. Establishing the trait-specific nature of variability in sleep/wake parameters could elucidate genetic mechanisms. [less ▲]

Detailed reference viewed: 22 (3 ULiège)
Peer Reviewed
See detailSensation de fatigue et performances cognitives: un lien spécifique dans la Sclérose en Plaques
Guillemin, Camille ULiege; LOMMERS, Emilie ULiege; DELRUE, Gaël ULiege et al

Conference (2018, September 20)

Introduction. La fatigue constitue un des symptômes les plus fréquents et invalidants des patients atteints de sclérose en plaques (SEP). Toutefois, le lien entre sensation subjective de fatigue et ... [more ▼]

Introduction. La fatigue constitue un des symptômes les plus fréquents et invalidants des patients atteints de sclérose en plaques (SEP). Toutefois, le lien entre sensation subjective de fatigue et déficits cognitifs reste actuellement peu clair. L'objectif de cette étude était donc d'investiguer la présence d'associations entre performances cognitives et mesures subjectives de fatigue physique et mentale. Des analyses de régression multiples stepwise ont été réalisées afin de déterminer la contribution respective des scores de fatigue physique et mentale, de dépression et d'anxiété aux performances cognitives des patients. Méthode: 38 patients SEP (EDSS : 1 à 6) et 29 sujets de contrôle appariés au niveau de l'âge et du sexe ont été inclus. Les scores de fatigue mentale et physique ont été obtenus sur base de la Modified-Fatigue Impact Scale (M-FIScog et M-FISphys) et les niveaux d'anxiété et de dépression au moyen de l'échelle HAD. Les performances cognitives ont été évaluées via des mesures de mémoire de travail (Indice de Mémoire de Travail (IMT) de la WAIS III), de mémoire épisodique verbale (total des 5 essais d¿apprentissage du CVLT) et visuelle (score de rappel immédiat au test 10/36), de vitesse de traitement (Indice de Vitesse de Traitement (IVT) de la WAIS III, Symbol Digit Modality Test, vitesse de dénomination et de lecture à l'épreuve de Stroop), et de fonctionnement exécutif (indice d'interférence à l'épreuve de Stroop). Les scores cognitifs ont été convertis en notes standard afin de prendre en compte la distribution d'âge et de niveau d'étude des participants. Résultats: Chez les patients SEP, le score M-FIScog a été retenu comme explicateur de la performance à l'IVT (R² :0.12, p<0.05), aux conditions dénomination (R² : 0.17, p<0.05) et interférence (R² :0.32, p<0.0005) du test de Stroop. Pour le groupe contrôle, aucune variable étudiée n'était significative, pour les 8 scores cognitifs présentés. Discussion: Ces résultats soulignent l'importance de distinguer fatigue mentale et fatigue physique dans la SEP, seule la fatigue mentale apparaissant un explicateur de la performance cognitive. L'influence de la fatigue mentale semble spécifique à la SEP pour des tâches simples impliquant la vitesse de traitement, et se révélant accrue lorsqu'un contrôle exécutif est requit. [less ▲]

Detailed reference viewed: 131 (8 ULiège)
Peer Reviewed
See detailSubjective feeling of fatigue and cognitive performances: a specific link in Multiple Sclerosis
Guillemin, Camille ULiege; LOMMERS, Emilie ULiege; DELRUE, Gaël ULiege et al

Poster (2018, September 13)

Introduction. Fatigue is one of the most frequent and debilitating symptom reported by patients with Multiple Sclerosis (MS). Yet, the link between cognitive impairments and subjective feeling of fatigue ... [more ▼]

Introduction. Fatigue is one of the most frequent and debilitating symptom reported by patients with Multiple Sclerosis (MS). Yet, the link between cognitive impairments and subjective feeling of fatigue remains unclear. This study aims to investigate the associations between cognitive performance and subjective measures of both physical and mental fatigue. Stepwise regression analyses were conducted in order to determine, correspondingly, the contribution of physical and cognitive fatigue scores, as well as depression and anxiety scores, on patients' cognitive performance. Methods. 38 MS patients (EDSS: 1 to 6) and 28 healthy controls, matched on age and sex, were included in this study. Cognitive and physical fatigue scores were obtained from the Modified-Fatigue Impact Scale (M-FIScog and M-FISphys), and anxiety and depression level were determined from the HAD scale. Cognitive performance was assessed for working memory (Working Memory Index (WMI) from the WAIS III), verbal episodic memory (sum of the 5 learning trials of the CVLT), visual episodic memory (immediate recall score of the 10/36 test), processing speed (Processing Speed Index (PSI) from the WAIS-IV, Symbol Digit Modality Test (SDMT), denomination and reading speed at the Stroop task) and executive functioning (interference score of the Stroop task). In order to take participants' age distribution and education levels into account, cognitive scores were converted into standard scores. Results. For MS patients, M-FIScog scores explained variance in performance for PSI (R² :0.12, p<0.05), and for denomination (R² : 0.17, p<0.05) and interference (R² :0.32, p<0.0005) scores of the Stroop task. Regarding the control group, no variable was significant for each 8 cognitive scores. M-FISphys, depression and anxiety scores were retained by none of the significant model. Discussion. These results stress the need to dissociate cognitive and physical fatigue in MS. Only cognitive fatigue appeared as an explanatory variable of cognitive performance. Moreover, the influence of cognitive fatigue seems to be MS-specific for task relying on processing speed, and accentuated when the task requires executive control. [less ▲]

Detailed reference viewed: 140 (5 ULiège)
Full Text
Peer Reviewed
See detailInter- and intra-expert variability in sleep scoring: comparison between visual and automatic analysis
Muto, Vincenzo ULiege; Berthomier, Christian; Schmidt, Christina ULiege et al

in Journal of Sleep Research. Supplement (2018, September 11)

Detailed reference viewed: 19 (2 ULiège)
Peer Reviewed
See detailArousals during sleep are associated with brain tau and amyloid-β burden in healthy older adults
Chylinski, Daphné ULiege; Rudzik, Franziska; Coppieters't Wallant, Dorothe ULiege et al

Conference (2018, September)

Detailed reference viewed: 66 (26 ULiège)