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See detailThe 19 Feb. 2016 Outburst of Comet 67P/CG: An ESA Rosetta Multi-Instrument Study
Grün, E.; Agarwal, J.; Altobelli, N. et al

in Monthly Notices of the Royal Astronomical Society (2016)

On 19 Feb. 2016 nine Rosetta instruments serendipitously observed an outburst of gas and dust from the nucleus of comet 67P/Churyumov-Gerasimenko. Among these instruments were cameras and spectrometers ... [more ▼]

On 19 Feb. 2016 nine Rosetta instruments serendipitously observed an outburst of gas and dust from the nucleus of comet 67P/Churyumov-Gerasimenko. Among these instruments were cameras and spectrometers ranging from UV over visible to microwave wavelengths, in-situ gas, dust and plasma instruments, and one dust collector. At 9:40 a dust cloud developed at the edge of an image in the shadowed region of the nucleus. Over the next two hours the instruments recorded a signature of the outburst that significantly exceeded the background. The enhancement ranged from 50% of the neutral gas density at Rosetta to factors >100 of the brightness of the coma near the nucleus. Dust related phenomena (dust counts or brightness due to illuminated dust) showed the strongest enhancements (factors >10). However, even the electron density at Rosetta increased by a factor 3 and consequently the spacecraft potential changed from ˜-16 V to -20 V during the outburst. A clear sequence of events was observed at the distance of Rosetta (34 km from the nucleus): within 15 minutes the Star Tracker camera detected fast particles (˜25 m s[SUP]-1[/SUP]) while 100 μm radius particles were detected by the GIADA dust instrument ˜1 hour later at a speed of ~6 m s[SUP]-1[/SUP]. The slowest were individual mm to cm sized grains observed by the OSIRIS cameras. Although the outburst originated just outside the FOV of the instruments, the source region and the magnitude of the outburst could be determined. [less ▲]

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See detailRat heart-aorta cluster transplantation : a novel model to study transplant rejection
D'Silva, Milbhor; Candidas, D.; Lee, S. et al

in Transplant International (1995), (8), 298-306

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See detailCharacterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.
Peers, Bernard ULiege; Johnson, T.; Ferreri, K. et al

in Molecular Endocrinology (1993), 7(10), 1275-83

The endocrine pancreas consists of several differentiated cell types that are distinguished by their selective expression of peptide hormones such as insulin, glucagon, and somatostatin. Although a number ... [more ▼]

The endocrine pancreas consists of several differentiated cell types that are distinguished by their selective expression of peptide hormones such as insulin, glucagon, and somatostatin. Although a number of homeobox-type factors have been proposed as key regulators of individual peptide genes in the pancreas, their cellular distribution and relative abundance remain uncharacterized. Also, their overlapping DNA binding specificities have further obscured the regulatory functions these factors perform during development. In this report we characterize a novel homeobox-type somatostatin transactivating factor termed STF-1, which is uniformly expressed in cells of the endocrine pancreas and small intestine. The 283-amino acid STF-1 protein binds to tissue-specific elements within the somatostatin promoter and stimulates somatostatin gene expression both in vivo and in vitro. Remarkably, STF-1 comprises the predominant tissue-specific element-binding activity in nuclear extracts from somatostatin-producing pancreatic islet cells, suggesting that this protein may have a primary role in regulating peptide hormone expression and specifying endocrine cell lineage in the developing gut. [less ▲]

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See detailFlexible Technique for Multiple Organ Procurement in Rats: A Training and Research Tool in Transplantation
D'Silva, M.; Pirenne, J.; Bonnet, Pierre ULiege et al

in Microsurgery (1993), 14(5), 342-9

Multiple organ procurement techniques are increasingly popular in many transplant centers. This paper describes a technique for multiorgan unit(s) explantation in rats. The procedure involves in situ ... [more ▼]

Multiple organ procurement techniques are increasingly popular in many transplant centers. This paper describes a technique for multiorgan unit(s) explantation in rats. The procedure involves in situ preliminary dissection, cold perfusion of the thoracic and abdominal organ units as separate procedures, explantation, and finally the ex situ isolation of various organ units as single and/or multiple organ combination units. The procedure is feasible, allows for flexibility in the separation of combination organ units, and is reproducible. The exercise is provided as a training and research tool for clinical and research transplant surgeons. The technique is also presented as an animal model for clinical organ sharing. [less ▲]

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See detailA technique for multiorgan harvesting in rats--an educational tool in transplantation
D'Silva, Milbhor; Pirenne, Jacques; Bonnet, Pierre ULiege et al

in Transplantation Proceedings (1991), 23(5), 2692

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