References of "Beaudart, Charlotte"
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See detailFrench translation and validation of the Cumberland Ankle Instability Tool, an instrument for measuring functional ankle instability
Geerinck, Anton ULiege; Beaudart, Charlotte ULiege; Salvan, Quentin et al

in Foot and Ankle Surgery (in press)

Background: Ankle sprains are one of the most common musculoskeletal injuries, and can lead to chronic ankle instability (CAI). The Cumberland Ankle Instability Tool (CAIT) measures a subset of CAI ... [more ▼]

Background: Ankle sprains are one of the most common musculoskeletal injuries, and can lead to chronic ankle instability (CAI). The Cumberland Ankle Instability Tool (CAIT) measures a subset of CAI, functional ankle instability (FAI).Because no French version existed, we set out to translate and validate the CAIT in French. Methods: The CAIT was translated using a forward-backward methodology. We examined its psychometric properties and calculated a cut-off score for FAI in a sample of 102 subjects (median age 22 years). Results: The CAIT was translated without significant problems. The CAIT-F can discriminate between those with and without FAI (p<0.001), with a cut-off score of ≤23 points. The test-retest reliability is excellent (ICC=0.960), as is the internal consistency (α=0.885). Construct validity was confirmed. No floor or ceiling effects were detected among subjects with FAI. Conclusions: The CAIT is now available in French, and is a valid and reliable instrument. [less ▲]

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See detailAssociation between dietary nutrient intake and sarcopenia in the SarcoPhAge study
Beaudart, Charlotte ULiege; Locquet, Médéa ULiege; Touvier, M. et al

in Aging Clinical and Experimental Research (in press)

Background: It has been suggested that a balanced nutritional intake may be useful in preventing or even reversing sarcopenia. Aim: To describe cross-sectional associations between dietary nutrient intake ... [more ▼]

Background: It has been suggested that a balanced nutritional intake may be useful in preventing or even reversing sarcopenia. Aim: To describe cross-sectional associations between dietary nutrient intake and sarcopenia. Methods: Subjects recruited from the SarcoPhAge study population completed a food frequency questionnaire. The micronutrient and macronutrient intake was evaluated in both sarcopenic and non-sarcopenic participants. The Nutritional Belgian Recommendations of 2016 were used, i.e., adequate intake and estimated average requirement (EAR). For micronutrients, the prevalence of insufficient intake was estimated as the proportion of subjects whose intake was below the EAR. Results: A total of 331 subjects (mean age of 74.8 ± 5.9 years, 58.9% women) had complete data and were included in this study. Among them, 51 were diagnosed with sarcopenia (15.4%). In the fully adjusted model, analyses revealed that sarcopenic subjects consumed significantly lower amounts of two macronutrients (proteins, lipids) and five micronutrients (potassium, magnesium, phosphorus, iron, and vitamin K) than non-sarcopenic subjects (all p values < 0.005). A significantly increased prevalence of insufficiency was found for sarcopenic subjects compared to non-sarcopenic subjects for potassium, magnesium, iron, calcium and vitamins E and C (all p values < 0.005). The prevalence of sarcopenic subjects who were also below the Nutritional Belgian Recommendations for protein and lipids was significantly higher than that of non-sarcopenic subjects. Discussion and conclusions: Sarcopenic subjects seem to consume significantly reduced amounts of many micronutrients and macronutrients compared to non-sarcopenic subjects. These results suggest that a poorly balanced diet may be associated with sarcopenia and poor musculoskeletal health, although prospective studies are needed to confirm these findings. © 2019, Springer Nature Switzerland AG. [less ▲]

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See detailCross-cultural adaptation, translation, and validation of the functional assessment scale for acute hamstring injuries (FASH) questionnaire for French-speaking patients
Locquet, Médéa ULiege; Willems, Tom; Specque, Clément et al

in Disability and Rehabilitation (in press)

Study design: This consisted of a translation and validation study. Background: Acute hamstring injury is a frequent muscle strain in sports that require high explosive strength, impulsion or running ... [more ▼]

Study design: This consisted of a translation and validation study. Background: Acute hamstring injury is a frequent muscle strain in sports that require high explosive strength, impulsion or running phases. Therefore, the Functional Assessment Scale for Hamstring Injury questionnaire was developed to assess pain, physical activity level and ability to perform various exercises in patients with hamstring injuries. The Functional Assessment Scale for Hamstring Injury questionnaire is currently available in English, German, and Greek. Objectives: The goal of this study was to provide a cross-culturally adapted French-translation of the FASH questionnaire and to assess its psychometric performance. Methods: The French-translation and cross-cultural adaptation process were based on international recommendations, following six rigorous steps: (a) two initial translations from English to French; (b) synthesis of the two translations; (c) back-translations; (d) comparisons between the back-translations and the original questionnaire by an expert committee; (e) pretest; and (f) approval of the final French version of the Functional Assessment Scale for Hamstring Injury questionnaire. To validate this French version, 116 subjects (17 pathological patients, 19 patients with other muscle injury, 40 athletes at risk, and 40 healthy control athletes) were recruited to complete the Functional Assessment Scale for Hamstring Injury questionnaire. The Short Form Health Survey (SF-36) was used as a comparative questionnaire. The psychometric properties of the questionnaire were evaluated by determining the test-retest reliability after a 48–60-h interval, internal consistency, construct validity, and floor/ceiling effects. Results: All of the items of the Functional Assessment Scale for Hamstring Injury questionnaire were translated without any major difficulties. The questionnaire showed excellent discriminative power by obtaining significantly different scores from the four groups (p¼0.01). Regarding psychometric performances, the test–retest reliability was excellent (IntraClass Coefficient Correlation of 0.997). Very high internal consistency was also observed (Cronbach’s alpha of 0.969). Correlations with the physical health subscales of the SF-36 were significant and considered to be strong, indicating an excellent convergent validity. The other subscales of the SF-36 (mental health) were weakly correlated with the FASH, reflecting good divergent validity. No floor or ceiling effects were observed. Conclusion: The French-translation of the Functional Assessment Scale for Hamstring Injury questionnaire and its cross-cultural adaptation can be considered to be successful. Functional Assessment Scale for Hamstring Injury-French questionnaire is now a reliable and valid tool for patients suffering from acute hamstring injury, and its application in clinical practice is particularly relevant. IMPLICATIONS FOR REHABILITATION The FASH-F can be considered to be discriminant, reliable and valid for the evaluation of the severity of symptoms and sports ability in individuals with hamstring injuries. FASH-F is now a reliable and valid tool for French-speaking patients suffering from acute hamstring injury, and its application in clinical practice is particularly relevant. A limitation of our study could be that the distribution between the different study groups was not homogeneous implying that our findings may not be fully representative of the general population. [less ▲]

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See detailFrench translation and validation of the exercise-induced leg pain Questionnaire
Beaudart, Charlotte ULiege; Hagelstein, Thibaut; Van Beveren, Julien et al

in Disability and Rehabilitation (in press)

Objective: The “Exercise-Induced Leg Pain” questionnaire was developed (in German) for the evaluation of the severity of symptoms and sports ability in individuals with exercise-induced leg pain. The ... [more ▼]

Objective: The “Exercise-Induced Leg Pain” questionnaire was developed (in German) for the evaluation of the severity of symptoms and sports ability in individuals with exercise-induced leg pain. The purpose of the present study was to translate and cross-culturally adapt this questionnaire into French and to study the reliability and validity of this French-language version. Methods: The translation and cross-cultural adaptation of the original “Exercise-Induced Leg Pain” was performed according to established guidelines. The translation part was carried out in six stages: (i) two initial translations from German to French; (ii) synthesis of the two translations; (iii) backward translations; (iv) comparison between the backward translations and the original questionnaire by an expert committee; (v) pretest; and (vi) approval of the final version of the French-language “Exercise-Induced Leg Pain” questionnaire. To validate this questionnaire, 84 subjects were recruited (28 pathological patients with a confirmed diagnosis of chronic leg pain, 28 asymptomatic sport students, and 28 healthy control athletes). The discriminative power of the questionnaire was tested, as well as its reliability (internal consistency and test–retest reliability after a 7–10-day interval), construct validity and floor/ceiling effects. Results: The French version of the “Exercise-Induced Leg Pain” questionnaire was generated without any major difficulties. The ability of the questionnaire to discriminate between the three groups of subjects was demonstrated with a total score of 61.0 ± 18.5 for the pathologic group; 93.9 ± 7.57 for the asymptomatic group and 94.1 ± 9.79 for the control group. A high internal consistency (Cronbach's alpha of 0.93) and an excellent test–retest reliability [intraclass coefficient correlation: 0.98 (95% confidence interval: 0.97–0.99, p < 0.001)] indicated that the “Exercise-Induced Leg Pain” is reliable. The questionnaire also demonstrated good construct validity against different subscales of the Short Form-36 questionnaire, a generic quality of life questionnaire, with more than 87% of the prespecified hypotheses confirmed. Finally, no floor effects or ceiling effects were observed. Conclusion: The French version of the « Exercise-Induced Leg Pain » was successfully translated and cross-culturally adapted. The questionnaire is consistent, valid and reliable for evaluating French-speaking patients with chronic exercise-induced leg pain. Implications for rehabilitation The “Exercise-Induced Leg Pain” questionnaire aims to assess the severity of symptoms that impact the function and sports ability of patients with exercise-induced leg pain; The French version of the « Exercise-Induced Leg Pain » was successfully translated and cross-culturally adapted. The questionnaire is consistent, valid and reliable for evaluating French-speaking patients with chronic exercise-induced leg pain. [less ▲]

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See detailThe explicit use of PRISMA and its effect on the reporting completeness of meta-analyses in the field of behavioral and social sciences
Leclercq, Victoria ULiege; Beaudart, Charlotte ULiege; Ajamieh, Sara ULiege et al

Poster (2019, May 14)

Objectives: To investigate the effect of the explicit use of PRISMA, a statement designed to help authors to report meta-analyses (MAs), on the reporting quality of MAs in behavioral and social sciences ... [more ▼]

Objectives: To investigate the effect of the explicit use of PRISMA, a statement designed to help authors to report meta-analyses (MAs), on the reporting quality of MAs in behavioral and social sciences. Methods: We evaluated a random sample of 207 MAs indexed in PsycINFO in 2016; 100 explicitly used PRISMA and 107 did not. Two authors independently checked the 27 PRISMA items and extracted factors that could potentially be associated with reporting quality. Results: From our 207 MAs, perfect adherence to PRISMA was found in less than 4%, of which 87% explicitly used PRISMA. The following items were significantly more frequently encountered in MAs that explicitly used PRISMA: structured summary, protocol and registration, information sources, search strategy, study characteristics, results of individual studies, funding, study selection, risk of bias in individual study and bias across studies. The journals’ impact factors, the endorsement of PRISMA by the journal, the number of authors, the country of the first author, the open access of the article and the design of the studies were significantly and positively associated with the explicit PRISMA use. Conclusions: Even if far from optimal, the explicit use of PRISMA has a positive influence on the reporting completeness of MAs. [less ▲]

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See detailThe methodological quality of meta-analyses in behavioral and social sciences: leads for enhancements according to AMSTAR 2
Leclercq, Victoria ULiege; Beaudart, Charlotte ULiege; Ajamieh, Sara ULiege et al

Poster (2019, May 14)

Objectives: To investigate the methodological quality in meta-analyses (MAs) published in behavioral and social sciences. Methods: We evaluated a random sample of 207 MAs indexed in PsycINFO database in ... [more ▼]

Objectives: To investigate the methodological quality in meta-analyses (MAs) published in behavioral and social sciences. Methods: We evaluated a random sample of 207 MAs indexed in PsycINFO database in 2016. Two authors independently extracted methodologic characteristics of all MAs with the 16 items of AMSTAR2 (A MeaSurement Tool to Assess systematic Reviews 2). AMSTAR2 allows to assess the methodological quality of MAs that classifies them in 4 categories: critically low, low, moderate and high. Results: From the 207 MAs, according to AMSTAR2 criteria, 95% of MAs were rated as critically low. Statistical methods were appropriate and publication bias well evaluated in respectively 87% and 70% of the MAs. However, much improvement is needed in data collection and analysis: Publication of the research protocol (in 11% of MAs), comprehensive literature search strategy (44%), assessment (37%) and interpretation (29%) of risk of bias in individual included studies and presentation of excluded studies (11%). Conclusions: The methodological quality of MAs of our sample was critically low, according to AMSTAR2 criteria. Some efforts could improve tremendously the methodological quality of behavioral and social sciences MAs and thus gain in robustness and reliability. [less ▲]

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See detailPatients’ preferences for osteoarthritis treatment: the value of stated-preference studies.
Hiligsmann, M.; Pinto, D.; Dennison, E et al

in Aging Clinical and Experimental Research (2019), 31(1), 1-3

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See detailAssessment of muscle function and physical performance in daily clinical practice: a position paper endorsed by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).
Beaudart, Charlotte ULiege; Rolland, Y.; Cruz-Jentoft, A.J. et al

in Calcified Tissue International (2019)

It is well recognized that poor muscle function and poor physical performance are strong predictors of clinically relevant adverse events in older people. Given the large number of approaches to measure ... [more ▼]

It is well recognized that poor muscle function and poor physical performance are strong predictors of clinically relevant adverse events in older people. Given the large number of approaches to measure muscle function and physical performance, clinicians often struggle to choose a tool that is appropriate and validated for the population of older people they deal with. In this paper, an overview of different methods available and applicable in clinical settings is proposed. This paper is based on literature reviews performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) working group on frailty and sarcopenia. Face-to-face meetings were organized afterwards where the whole group could amend and discuss the recommendations further. Several characteristics should be considered when choosing a tool: (1) purpose of the assessment (intervention, screening, diagnosis); (2) patient characteristics (population, settings, functional ability, etc.); (3) psychometric properties of the tool (test–retest reliability, inter-rater reliability, responsiveness, floor and ceiling effects, etc.); (4) applicability of the tool in clinical settings (overall cost, time required for the examination, level of training, equipment, patient acceptance, etc.); (5) prognostic reliability for relevant clinical outcomes. Based on these criteria and the available evidence, the expert group advises the use of grip strength to measure muscle strength and the use of 4-m gait speed or the Short Physical Performance Battery test to measure physical performance in daily practice. The tools proposed are relevant for the assessment of muscle weakness and physical performance. Subjects with low values should receive additional diagnostic workups to achieve a full diagnosis of the underlying condition responsible (sarcopenia, frailty or other). [less ▲]

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See detailSafety of topical non-steroidal anti-inflammatory drugs in osteoarthritis: outcomes of a systematic review and meta-analysis.
Honvo, Germain ULiege; Leclercq, Victoria ULiege; Geerinck, Anton ULiege et al

in Drugs and Aging (2019), 36(suppl 1), 45-64

Objective: We aimed to assess the safety of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized, placebo ... [more ▼]

Objective: We aimed to assess the safety of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized, placebo-controlled trials. Methods: A comprehensive literature search was undertaken in the MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and Scopus electronic databases. Randomized, double-blind, placebo-controlled, parallel-group trials that assessed adverse events (AEs) with topical NSAIDs in patients with OA were eligible for inclusion. Authors and/or study sponsors were contacted to obtain the full report of AEs. The primary outcomes were overall severe and serious AEs, as well as the following MedDRA System Organ Class (SOC)-related AEs: gastrointestinal, vascular, cardiac, nervous system, skin and subcutaneous tissue, musculoskeletal and connective tissue. Results The search strategy identified 1209 records, from which 25 papers were included in the qualitative synthesis and 19 were included in the meta-analysis, after exclusions. Overall, more total AEs (odds ratio [OR] 1.16, 95% confidence interval [CI] 1.04–1.29; I2 = 0.0%) and more withdrawals due to AEs (OR 1.49, 95% CI 1.15–1.92; I2 = 0.0%) were observed with topical NSAIDs compared with placebo. The same results were achieved with topical diclofenac, largely driven by an increase in skin and subcutaneous tissue disorders (OR 1.73, 95% CI 0.96–3.10), although the difference was not statistically significant compared with placebo. No significant difference in the odds for gastrointestinal disorders was observed between topical NSAIDs and placebo (OR 0.96, 95% CI 0.73–1.27). Conclusions Topical NSAIDs may be considered safe in the management of OA, especially with regard to low gastrointestinal toxicity. The use of topical NSAIDs in OA should be considered, taking into account their risk: benefit profile in comparison with other anti-OA treatments. [less ▲]

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See detailEWGSOP2 versus EWGSOP1: impact of the prevalence of sarcopenia and its major health consequences.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Petermans, Jean ULiege et al

in Journal of the American Medical Directors Association (2019), 20(3), 384-385

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See detailThree-Year Adverse Health Consequences of Sarcopenia in Community-Dwelling Older Adults According to 5 Diagnosis Definitions
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Hajaoui, Manon ULiege et al

in Journal of the American Medical Directors Association (2019), 20

Objectives: To assess the occurrence of 3 major adverse outcomes of sarcopenia (ie, physical disabilities, institutionalizations and deaths) observed over a 3-year follow-up in older adults and compare ... [more ▼]

Objectives: To assess the occurrence of 3 major adverse outcomes of sarcopenia (ie, physical disabilities, institutionalizations and deaths) observed over a 3-year follow-up in older adults and compare the risk of these outcomes using 5 definitions of sarcopenia. Design: The study is a part of the ongoing SarcoPhAge (for Sarcopenia and Physical Impairment with advancing Age) longitudinal project. Setting and Participants: The SarcoPhAge study follows 534 community-dwelling older adults. Measures: Sarcopenia was defined as low muscle mass plus a decreased muscle function. Data on adverse outcomes were collected yearly during the annual follow-up or with a phone call. The association between baseline sarcopenia and the occurrence of undesirable outcomes was tested using the Cox proportional hazards model or a logistic regression model. Results: A total of 534 subjects were recruited into this prospective cohort (73.5 6.2 years, 60.5% female). After 3 years, 33 participants were lost to follow-up. If no association between baseline sarcopenia and physical disabilities or institutionalizations was highlighted, a higher number of deaths occurred in individuals diagnosed with sarcopenia than in those who were not diagnosed (16.2% vs 4.6%, P value <.001). The probability of death within 3 years when presenting with sarcopenia showed an approximately 3-fold increase compared to subjects without sarcopenia. Conclusion: Over a 3-year period, sarcopenia at baseline was associated with an increased risk of mortality. There were some variations in the ability of different definitions of sarcopenia to predict outcomes. [less ▲]

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See detailAssociation between the decline in muscle health and the decline in bone health in older individuals from the SarcoPhAge Cohort.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Reginster, Jean-Yves ULiege et al

in Calcified Tissue International (2019), 104

The longitudinal relationship between bone health and muscle health is scarcely explored. We aimed to explore the Relationship between bone decline and muscle decline over 1 year in older individuals. We ... [more ▼]

The longitudinal relationship between bone health and muscle health is scarcely explored. We aimed to explore the Relationship between bone decline and muscle decline over 1 year in older individuals. We used data from the SarcoPhAge cohort, which aims to identify the consequences of sarcopenia. In this way, this study also highlights the yearly changes in muscle mass (by dual-energy absorptiometry), muscle weakness (by grip strength), and/or physical performance (by the short physical performance battery test). Measurements of areal bone mineral density (aBMD), enabling the diagnosis of osteoporosis, and bone microarchitecture (by means of the trabecular bone score) were also performed each year. A 1-year clinically relevant decline in bone and muscle health components was evidenced using the Edwards–Nunnally index. Among the 232 participants with complete data (75.5 ± 5.4 years, 57.8% women), we observed an association between a clinically relevant decline in the skeletal muscle mass index (SMI) and a decrease in aBMD (adjusted OR = 2.12 [1.14–2.51] for the spine, 2.42 [1.10–5.34] for the hip and 2.12 [1.04–5.81] for the neck), as well as a significant association between SMI and deterioration of the skeletal microarchitecture (aOR = 3.99 [2.07–7.70]). A clinically relevant decline in muscle strength was associated with a decrease in spine aBMD (aOR = 2.93 [1.21–7.12]) and hip aBMD (aOR = 3.42 [1.37–7.64]) only. The decline in muscle performance was related to the decline in bone microarchitecture only (aOR = 2.52 [1.23–5.17]). Individuals with incident sarcopenia had an approximately fivefold higher risk of concomitantly developing osteoporosis. A dynamic relationship between impaired muscle and bone health was observed, with an obvious association between the concomitant incidences of osteoporosis and sarcopenia. [less ▲]

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See detailThe health economics burden of sarcopenia: a systematic review
Bruyère, Olivier ULiege; Beaudart, Charlotte ULiege; Ethgen, Olivier ULiege et al

in Maturitas (2019), 119

Despite of better knowledge about sarcopenia, an optimal understanding of its consequences from a public health perspective remains a challenge. Specifically, the economic burden of the illness is unclear ... [more ▼]

Despite of better knowledge about sarcopenia, an optimal understanding of its consequences from a public health perspective remains a challenge. Specifically, the economic burden of the illness is unclear. As a support for the public health policy makers and other health actors, our objective was to perform a systematic review of the literature comparing healthcare costs between sarcopenic and non-sarcopenic patients (under the registration number CRD42018099291). A research of relevant articles was conducted among electronical databases (MEDLINE and Scopus). Rigorous eligibility criteria were established (e.g., subjects with sarcopenia, both men and women,mean age of the sarcopenic population) and applied by two investigators to include suitable studies. The narrative report described that, at the first screening phase, performed by 2 independent reviewers, covered 455 references. Finally, 14 relevant studies have been included in the analysis. Overall, we noted an important heterogeneity between studies in the way of assessing sarcopenia (i.e. operational definitions, tools and cut-offs used). There were also large variation between studies in their cost analysis settings (i.e., discrepancies in time horizon, type and source of economic data). Most of the studies focused on hospitalization costs following a surgery for a specific disease such as cancer. Finally, 11 out of 14 studies tended to report higher health care costs in sarcopenic patients. However, most of the included studies have important methodological bias (i.e. potential confusion factors rarely taken into account), with a low to moderate quality scores. More standardized research, taking into account all limitations of the current studies, should be conducted to assess the true impact of sarcopenia on health care consumption. [less ▲]

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See detailTranslation and validation of the Dutch SarQoL, a quality of life questionnaire specific to sarcopenia
Geerinck, Anton ULiege; Scheppers, Annelies; Beaudart, Charlotte ULiege et al

in Journal of Musculoskeletal and Neuronal Interactions (2018), 18(4)

OBJECTIVES: To translate the Sarcopenia Quality of Life (SarQoL®) questionnaire into Dutch and to evaluate the psychometric properties of the Dutch version of this questionnaire. METHODS: The translation ... [more ▼]

OBJECTIVES: To translate the Sarcopenia Quality of Life (SarQoL®) questionnaire into Dutch and to evaluate the psychometric properties of the Dutch version of this questionnaire. METHODS: The translation was carried out using a 5-step process, with 2 initial translations, a merging of these 2 translations, 2 backwards translations, an expert committee review and a pretest of the questionnaire. Sarcopenia was diagnosed with the EWGSOP algorithm. The validation consisted of an examination of the discriminative power, internal consistency, construct validity, test-retest reliability and floor and ceiling effects. RESULTS: No significant problems were encountered during the translation process. A total of 92 subjects were included in the validation part of this study, 30 of which were sarcopenic. Discriminative power between sarcopenic and nonsarcopenic subjects was found for all domains and the Overall score (median overall QoL score: 67.15 vs 79.72; p=0.003). High internal consistency was found (Cronbach’s alpha=0.883), as well as good construct validity with 75% of hypotheses confirmed. Test-retest reliability was excellent (ICC=0.976; 95% CI=0.947-0.989) and no floor or ceiling effects were observed. CONCLUSION: The Dutch version of the SarQoL® questionnaire is ready for use in clinical and research applications. [less ▲]

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See detailEvaluation of the responsiveness of the SarQoL® questionnaire, a patient-reported outcome measure specific to sarcopenia.
Geerinck, Anton ULiege; Bruyère, Olivier ULiege; Locquet, Médéa ULiege et al

in Advances in Therapy (2018), 35

INTRODUCTION: The Sarcopenia Quality of Life (SarQoL®) questionnaire was developed to provide a patient-reported outcome measure specific to sarcopenia. Its psychometric properties indicate that it is a ... [more ▼]

INTRODUCTION: The Sarcopenia Quality of Life (SarQoL®) questionnaire was developed to provide a patient-reported outcome measure specific to sarcopenia. Its psychometric properties indicate that it is a valid and reliable instrument. However, until now, its ability to detect change over time has not been examined. Therefore, the objective of this study is to evaluate the responsiveness (also known as sensitivity to change) of the SarQoL® questionnaire in a prospective, longitudinal cohort of community-dwelling, older, sarcopenic subjects. METHODS: Sarcopenic subjects from the SarcoPhAge (Sarcopenia and Physical impairment with advancing Age) study were included. Responsiveness was evaluated with nine pre-specified hypotheses on the correlation between the evolution of the SarQoL® scores after a 2-year interval and the evolution of the scores on the Short Form-36 (SF-36) and the Euroqol 5-dimension (EQ-5D) questionnaires. This technique considers responsiveness to be a form of longitudinal validity. Additionally, standardized response means were also calculated to compare the quantity of change measured by the different questionnaires. RESULTS: A total of 42 sarcopenic subjects were included. The median age of the sample was 72.9 (68.9-78.8) years, 59.5% were female, and the mean body mass index was 23.3 (20.4-25.7) kg/m2. A good responsiveness was observed, as evidenced by the confirmation of eight out of nine hypotheses, well above the 75% confirmation threshold. The standardized response mean of the Overall SarQoL® score was significantly higher than those of the SF-36 Physical Component Summary (p = 0.005), the EQ-5D Utility Index (p < 0.001) and the Euroqol visual analogue scale (p = 0.003). CONCLUSION: The first data available on the ability of the SarQoL® questionnaire to detect change over time indicates that the questionnaire has good responsiveness. This, together with the previously established psychometric properties, confirms that the SarQoL® questionnaire is a relevant instrument for the assessment of quality of life in sarcopenic populations. [less ▲]

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See detailThe use of PRISMA statement improves the reporting quality of meta-analyses published in the field of psychology
Leclercq, Victoria ULiege; Beaudart, Charlotte ULiege; Ajamieh, Sara ULiege et al

in Value in Health Regional Issues (2018, October), 21

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See detailTraduction et validation du questionnaire "Cumberland Ankle Instability Tool" en français
Kaux, Jean-François ULiege; Salvan, Quentin; Beaudart, Charlotte ULiege

in La voile et les sports nautiques (2018, September)

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