References of "Sacre, Pierre-Yves"
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See detailDetection of counterfeit Viagra by Raman microspectroscopy imaging and multivariate analysis
Sacré, Pierre-Yves ULiege; Deconinck, Eric; Saerens, Lien et al

Conference (2011, May 13)

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See detailImpurity fingerprints for the identification of counterfeit medicines - a feasibility study
Sacré, Pierre-Yves ULiege; Deconinck, Eric; Daszykowski, Michal et al

in Analytica Chimica Acta (2011), 701

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See detailDevelopment and validation of a ultra-high-performance liquid chromatography-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines
Sacré, Pierre-Yves ULiege; Deconinck, Eric; Chiap, Patrice ULiege et al

in Journal of Chromatography. A (2011), 1218

Pharmaceutical counterfeiting is a permanently growing problem. Control laboratories are constantly analysing counterfeit medicines. In industrialised countries, one of the main counterfeited class of ... [more ▼]

Pharmaceutical counterfeiting is a permanently growing problem. Control laboratories are constantly analysing counterfeit medicines. In industrialised countries, one of the main counterfeited class of medicines are erectile dysfunction drugs. This paper describes the development and validation of a fast method to detect and quantify the three authorised phosphodiesterase type 5 inhibitors and five analogues. The method is based on the use of a sub-2 microns polar-embedded column with a gradient using acetonitrile as organic modifier and 10 mM ammonium formate buffer (pH 3.5) as aqueous component of the mobile phase. The separation was achieved in less than 4.5 min. The method has also been compared to the registered HPLC method for the assay of Viagra® which was considered as the reference method. The method is also compatible with on-line coupling mass spectrometry and will significantly reduce analysis times and solvent consumption. [less ▲]

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See detailDetection of counterfeit Viagra® by Raman Microspectroscopy imaging and multivariate analysis.
Sacré, Pierre-Yves ULiege; Deconinck, Eric; Saerens, Lien et al

in Journal of Pharmaceutical and Biomedical Analysis (2011), 56

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See detailA fast Ultra High Pressure Liquid chromatographic method for qualification and quantification of pharmaceutical combination preparations containing paracetamol, acetyl salicylic acid and/or antihistaminics.
Deconinck, Eric; Sacre, Pierre-Yves ULiege; Baudewyns, Sébastien et al

in Journal of Pharmaceutical and Biomedical Analysis (2011), 56

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See detailComparison and combination of spectroscopic techniques for the detection of counterfeit medicines
Sacré, Pierre-Yves ULiege; Deconinck, Eric; De Beer, Thomas et al

Poster (2010, September 23)

During this study, Fourier transform infrared spectroscopy (FT-IR), near infrared spectroscopy (NIR) and Raman spectroscopy were applied to 55 samples of counterfeit and imitations of Viagra® and 39 ... [more ▼]

During this study, Fourier transform infrared spectroscopy (FT-IR), near infrared spectroscopy (NIR) and Raman spectroscopy were applied to 55 samples of counterfeit and imitations of Viagra® and 39 samples of counterfeit and imitations of Cialis®. The aim of the study was to investigate which of these techniques and associations of them were the best for discriminating genuine from counterfeit and imitation samples. Only the regions between 1800-400 cm-1 and 7000-4000 cm-1 were used for FT-IR and NIR spectroscopy respectively. Partial Least Square analysis has been used to allow the detection of counterfeit and imitation tablets. It is shown that for the Viagra® samples, the best results were provided by a combination of FT-IR and NIR spectroscopy. On the other hand, the best results for the Cialis® samples were provided by the combination of NIR and Raman spectroscopy (1400-1190 cm-1). These techniques permitted a clear discrimination between genuine and counterfeit or imitation samples but also the distinction of clusters among illegal samples. This might be interesting for forensic investigations by authorities. [less ▲]

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See detailComparison and combination of spectroscopic techniques for the detection of counterfeit medicines
Sacré, Pierre-Yves ULiege; Deconinck, Eric; De Beer, Thomas et al

in Journal of Pharmaceutical and Biomedical Analysis (2010), 53

During this study, Fourier transform infrared spectroscopy (FT-IR), near infrared spectroscopy (NIR) and Raman spectroscopy were applied to 55 samples of counterfeit and imitations of Viagra® and 39 ... [more ▼]

During this study, Fourier transform infrared spectroscopy (FT-IR), near infrared spectroscopy (NIR) and Raman spectroscopy were applied to 55 samples of counterfeit and imitations of Viagra® and 39 samples of counterfeit and imitations of Cialis®. The aim of the study was to investigate which of these techniques and associations of them were the best for discriminating genuine from counterfeit and imitation samples. Only the regions between 1800-400 cm-1 and 7000-4000 cm-1 were used for FT-IR and NIR spectroscopy respectively. Partial Least Square analysis has been used to allow the detection of counterfeit and imitation tablets. It is shown that for the Viagra® samples, the best results were provided by a combination of FT-IR and NIR spectroscopy. On the other hand, the best results for the Cialis® samples were provided by the combination of NIR and Raman spectroscopy (1400-1190 cm-1). These techniques permitted a clear discrimination between genuine and counterfeit or imitation samples but also the distinction of clusters among illegal samples. This might be interesting for forensic investigations by authorities. [less ▲]

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See detailIn vitro antiplasmodial activity of ethnobotanically selected plants from Burkina Faso
Jansen, Olivia ULiege; Angenot, Luc ULiege; Tits, Monique ULiege et al

in Planta Medica (2008), 74(9), 1142-1142

Detailed reference viewed: 63 (23 ULiège)