References of "FRANCHIMONT, Claudine"
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See detailThe skin landscape in diabetes mellitus. Focus on dermocosmetic management.
PIERARD, Gérald ULiege; Seite, Sophie; Hermanns-Lê, Trinh ULiege et al

in Clinical, Cosmetic and Investigational Dermatology (2013), 6

BACKGROUND: Some relationships are established between diabetes mellitus (DM) and a series of cutaneous disorders. Specific dermatoses are markers for undiagnosed DM. Other disorders represent supervening ... [more ▼]

BACKGROUND: Some relationships are established between diabetes mellitus (DM) and a series of cutaneous disorders. Specific dermatoses are markers for undiagnosed DM. Other disorders represent supervening complications in an already treated DM patient. OBJECTIVE: To review the information about dermocosmetic care products and their appropriate use in the management and prevention of dermatoses related to DM. METHOD: The peer-reviewed literature and empiric findings are covered. Owing to the limited clinical evidence available for the use of dermocosmetics, a review of the routine practices and common therapies in DM-related dermatoses was conducted. RESULTS: Some DM-related dermatoses (acanthosis nigricans, pigmented purpuric dermatosis) are markers of macrovascular complications. The same disorders and some others (xerosis, Dupuytren's disease) have been found to be more frequently associated with microangiopathy. Other skin diseases (alopecia areata, vitiligo) were found to be markers of autoimmunity, particularly in type 1 DM. Unsurprisingly, using dermocosmetics and appropriate skin care has shown objective improvements of some DM-related dermatoses, such effects improve the quality of life. The most common skin manifestations of DM fall along continuum between "dry skin," xerosis, and acquired ichthyosis, occurring predominately on the shins and feet. Dermocosmetic products improve the feeling of well-being for DM patients. [less ▲]

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See detailComment j'explore ... l'atteinte fonctionnelle cutanee d'une sclerodermie.
Hermanns-Lê, Trinh ULiege; Franchimont, Claudine ULiege; PIERARD, Gérald ULiege et al

in Revue Médicale de Liège (2013), 68(3), 141-7

Scleroderma refers to distinct clinical presentations sharing in common a sclerotic process most often clinically obvious on the skin. The involvement possibly affects the skin alone in morphea or in ... [more ▼]

Scleroderma refers to distinct clinical presentations sharing in common a sclerotic process most often clinically obvious on the skin. The involvement possibly affects the skin alone in morphea or in combination with internal lesions in systemic sclerosis. Some objective and non-invasive functional assessments are useful for better appreciating the severity and evolution of the disease, as well as to monitor the therapeutic efficacy. In this endeavour, in vivo measurements of the skin mechanical properties are unsurprisingly informative. [less ▲]

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See detailAlterations in hair follicle dynamics in women.
Franchimont, Claudine ULiege; PIERARD, Gérald ULiege

in BioMed Research International (2013), 2013(957432),

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See detailImmunohistochemical patterns in the interfollicular Caucasian scalps. Influence of age-, gender- and alopecia.
Franchimont, Claudine ULiege; Loussouarn, Genevière; Panhard, Ségolène et al

in BioMed Research International (2013), 2013(769489),

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See detailThe weather-beaten dorsal hand. Clinical rating, shadow casting optical profilometry and skin capacitance mapping.
Delvenne, Marie; FRANCHIMONT, Claudine ULiege; SEIDEL, Laurence ULiege et al

in BioMed Research International (2013), 2013

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See detailAnalytic dermoscopy of superficial basal cell carcinoma.
FRANCHIMONT, Claudine ULiege; Hermanns, Jean-Francois; Caucanas, Marie et al

in Journal of Case Reports in Medicine (2013), 3

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See detailIn vivo evaluation of the skin tensile strength by the suction method: pilot study coping with hysteresis and creep extension.
PIERARD, Gérald ULiege; Pierard, Sébastien ULiege; Delvenne, Philippe ULiege et al

in ISRN dermatology (2013), 2013

From an engineering standpoint, both the skin and subcutaneous tissue act as interconnected load-transmitting structures. They are subject to a variety of intrinsic and environmental influences. Changes ... [more ▼]

From an engineering standpoint, both the skin and subcutaneous tissue act as interconnected load-transmitting structures. They are subject to a variety of intrinsic and environmental influences. Changes in the cutaneous viscoelasticity represent an important aspect in a series of skin conditions. The aim of this work was to explore the methodology of biomechanical measurements in order to better appreciate the evolution and severity of some connective tissue diseases. The Cutometer MPA 580 (C+K electronic) was used in the steep and progressive suction procedures. Adapting measurement modalities was explored in order to mitigate any variability in data collection. The repeat steep suction procedure conveniently reveals the creep phenomenon. By contrast, the progressive suction procedure highlights the hysteresis phenomenon. These viscoelastic characteristics are presently described using the 2 and 4 mm probes on normal skin and in scleroderma, acromegaly, corticosteroid-induced dermatoporosis, and Ehlers-Danlos syndrome. The apposition of an additional outer contention on the skin altered differently the manifestations of the creep extension and hysteresis among the tested skin conditions. Any change in the mechanical test procedure affects the data. In clinical and experimental settings, it is mandatory to adhere to a strict and controlled protocol. [less ▲]

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See detailScrutinizing skinfield melanin patterns in young Caucasian women.
Hermanns-Lê, Trinh ULiege; Franchimont, Claudine ULiege; PIERARD, Gérald ULiege

in Expert Opinion on Medical Diagnostics (2013)

Introduction: When using adequate wavelength illumination and high resolution recordings, Caucasian skin color appears uneven. The patterns of faint mosaic melanoderma (FMM) are diverse and possibly ... [more ▼]

Introduction: When using adequate wavelength illumination and high resolution recordings, Caucasian skin color appears uneven. The patterns of faint mosaic melanoderma (FMM) are diverse and possibly related to the risk of skin cancer development. Areas covered: The current peer-reviewed publications about objective methods quantifying FMM are revisited. The images from the Visioscan(R) and Visioface(R) Quick devices are computerized in order to record the ultraviolet light-enhanced visualization (ULEV) and the color-enhanced visualization (CEV) of the skin. Previously published data regarding the FMM are gathered in 20 odd Caucasian women. Seven FMM patterns are distinguished. They appear expressed differently according to body regions, but the mean gray level appears more uniform. Expert opinion: The combination of larger subclinical melanotic macules and ivory spots during early adulthood is apparently associated with an increased risk for non-melanoma skin cancers. [less ▲]

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See detailThe thousand and one facets of actinic keratosis.
PIERARD, Gérald ULiege; FRANCHIMONT, Claudine ULiege; DELVENNE, Philippe ULiege

Book published by Nova Science Publishers (2013)

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See detailCritical assessment of diabetic xerosis.
PIERARD, Gérald ULiege; Franchimont, Claudine ULiege; Scheen, André ULiege

in Expert Opinion on Medical Diagnostics (2013), 7(2), 201-7

Introduction: Diabetes mellitus is commonly responsible for skin changes including discrete to mild xerosis. Areas covered: This review focuses on some selected relevant bioinstrumental methods assessing ... [more ▼]

Introduction: Diabetes mellitus is commonly responsible for skin changes including discrete to mild xerosis. Areas covered: This review focuses on some selected relevant bioinstrumental methods assessing diabetes xerosis. Peer-reviewed articles on objective non-invasive methods were scrutinized. The reviewed methods address i) the xerosis severity grading scale, ii) corneodynamics referring to the desquamation rate, iii) electrometric assessment of skin hydration including skin capacitance mapping and iv) implication of the imperceptible perspiration. The subjective clinical assessment often fails to disclose diabetic xerosis with confidence and precision. By contrast, a multipronged biometrological approach identifies a cluster of diabetic patients who experience alterations in the structural and functional maturation of the stratum corneum. Expert opinion: A multipronged biometrological approach helps identifying the changes in the stratum corneum of diabetic xerosis. There is a continuum between the 'dry skin' feeling, xerosis and ichthyosiform presentations, particularly on the shins and feet of diabetic patients. [less ▲]

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See detailCharacterization of spontaneous collagen fibrillogenesis in a cell-free and tension-free environment.
PIERARD, Gérald ULiege; Hermanns-Lê, Trinh ULiege; Delvenne, Philippe ULiege et al

in Clinical & Experimental Dermatology (2013)

The collagen fibril packing that forms threads and bundles is poorly defined, despite the fact that it is important for distinct aspects of the adventitial and reticular dermis. The present study explored ... [more ▼]

The collagen fibril packing that forms threads and bundles is poorly defined, despite the fact that it is important for distinct aspects of the adventitial and reticular dermis. The present study explored an in vitro fibrillogenesis model using the property of heat polymerization. The process was performed on glass slides with mixtures of collagen I and III, and the material was viewed by scanning electron microscopy. In all instances, collagen I and III formed fibrils with regular sizes. The formation of threads was influenced by the relative proportions of collagen I and III; increasing the relative proportion of collagen I resulted in the formation of threads showing increasing variations in thickness. These findings are in line with the differential presentation and compositions of the different parts of the dermis. The possible interventions of stromal cells and of other macromoleules of the extracellular matrix were not considered in this study. [less ▲]

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See detailSweaty skin, background and assessments.
Noël, Fanchon ULiege; Franchimont, Claudine ULiege; PIERARD, Gérald ULiege et al

in International Journal of Dermatology (2012), 51(6), 647-55

Overproduction of sweat, sweaty skin, and body malodors are felt unpleasant by many people in diverse social groups. This review summarizes the functional aspects of the eccrine, apocrine, and apoeccrine ... [more ▼]

Overproduction of sweat, sweaty skin, and body malodors are felt unpleasant by many people in diverse social groups. This review summarizes the functional aspects of the eccrine, apocrine, and apoeccrine sweat glands as encountered in health and disease. A series of measuring methods are conveniently used to explore any trouble in sweat production. These include the gravimetric method, water evaporation quantification, skin staining procedures, dye injections, casting replicas, average electrometric assessments, and skin capacitance mapping / imaging (SCM). Qualitative assessment is provided by collection of sweat and volatile compounds followed by chromatographic analysis. At present, SCM appears to be the most valuable method for assessing the number of active glands and their individual sweat production by the eccrine and apoeccrine glands. [less ▲]

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See detailDermatoses non infectieuses de la grossesse.
Hermanns-Lê, Trinh ULiege; Franchimont, Claudine ULiege; Delvenne, Philippe ULiege et al

in Thérapeutique Dermatologique (2012)

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See detailFondements physico-biologiques de la fluorescence cutanee - Revue.
SZEPETIUK, Grégory ULiege; FRANCHIMONT, Claudine ULiege; QUATRESOOZ, Pascale ULiege et al

in Pathologie Biologie (2012), 60

Fluorescence is a peculiar aspect of photoluminescence. Some intrinsic components of the skin are fluorophores. Other synthetic components are metabolized into fluorophores. These characteristics may be ... [more ▼]

Fluorescence is a peculiar aspect of photoluminescence. Some intrinsic components of the skin are fluorophores. Other synthetic components are metabolized into fluorophores. These characteristics may be used for identifying some specific aspects of skin physiopathology. Recent technological evolution has provided new devices bringing sensitive and specific information from the skin. This review presents a synthesis of the progress made in the field of fluorescence and specular reflexion of incident UV light on the skin. [less ▲]

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See detailFibromes cutanés.
PIERARD, Gérald ULiege; Franchimont, Claudine ULiege

in Fondation René Touraine (Ed.) Thérapeutique Dermatologique (2012)

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See detailToxic epidermal necrolysis and antifolate drugs in cancer chemotherapy.
Franchimont, Claudine ULiege; Lesuisse, Marianne; Humbert, Philippe et al

in Current Drug Safety (2012), 7(5), 357-60

Folates are one-carbon donors essential for synthesizing purines, pyrimidines, serine, and methionine. They correspond to anionic hydrophilic molecules essential for DNA synthesis in mammalian cells. The ... [more ▼]

Folates are one-carbon donors essential for synthesizing purines, pyrimidines, serine, and methionine. They correspond to anionic hydrophilic molecules essential for DNA synthesis in mammalian cells. The latter cells lack the capacity to synthesize folates. In some patients, high dosages of antifolate drugs (eg: methotrexate, pemetrexed) used in cancer chemotherapy alter the keratinocytes, endothelial cells and Factor XIIIa+ dermal dendrocytes in a range of various severities. Such conditions clinically designed under the heading antifolate cytotoxic skin reaction (ACSR) occasionally resemble the toxic epidermal necrolysis (TEN) / Stevens-Johnson syndrome (SJS) spectrum. Whether or not the TEN/SJS presentation of ACSR is a regular condition similar to that induced by other drugs or a variant condition supported by a unique pathomechanism is unsettled. [less ▲]

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See detailCold injuries.
PIERARD, Gérald ULiege; QUATRESOOZ, Pascale ULiege; FRANCHIMONT, Claudine ULiege

in Goldsmith, L.; Gilchrest, B; Katz, S (Eds.) et al Fitzpatrick's Dermatology in General Medicine (2012)

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See detailHow to manage hair changes in cancer patients.
FRANCHIMONT, Claudine ULiege; QUATRESOOZ, Pascale ULiege; RORIVE, Andrée ULiege et al

in Vereecken, P.; Awada, A. (Eds.) Handbook of skin care in cancer patients. (2012)

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See detailImpact climatique sur les ulcères veineux de jambe.
FRANCHIMONT, Claudine ULiege; Hermanns-Lê, Trinh ULiege; LESUISSE, Marianne et al

in Revue Médicale de Liège (2012), 67

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