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1: Early Hum
Dev. 1986 Feb;13(1):13-20.

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Brain growth in sick newborn infants: a clinical and real-time ultrasound
analysis.

Battisti
O, Bach
A, Gerard
P.

This study concerns 152 neonates admitted between June 1981
and December 1983 in a neonatal intensive care unit. It aims to evaluate brain
growth and to analyse the influence of intrauterine growth retardation (IUGR),
intracranial haemorrhage (ICH) and ventricular dilatation (VD) in pre-term
infants. The babies were first analysed at birth. The sample comprised 127
normal infants and 25 IUGR neonates. An ultrasonic index of cerebral growth
was devised: the height of the frontal lobes (HFL), measured in a standardised
coronal slice of the brain. According to gestational age (GA), HFL and head
circumference (HC) gave a similar assessment of brain growth. A regression
line of normal intrauterine values of HFL has been produced according to GA
and might be added to the other ways of following the intrauterine growth of
the brain after 26 weeks. Brain growth was slower in IUGR, when assessed both
by HFL and HC. The infants were also assessed during the postnatal period for
a mean period of 27.6 days (S.E.M.: 3.5). They were divided into 5 groups: 45
preterm infants without IUGR, ICH or VD; 45 preterm neonates with ICH alone;
12 preterm babies with ICH and VD alone, 10 preterm infants with isolated FGR,
and 8 preterm neonates with IUGR and ICH. A calculation of the global
anthropometric (body weight, body length, HC and HFL) weekly increment was
made for all infants according to their respective group. No statistical
difference in any of these parameters between these 5 groups emerged.(ABSTRACT
TRUNCATED AT 250 WORDS)

PMID: 3514201 [PubMed - indexed for MEDLINE]

Related Articles

Impact
of prematurity and intrauterine growth retardation on neonatal hemorrhagic
and ischemic brain damage. [Eur Neurol. 1993]

Intrauterine
growth retardation (IUGR) in pre-term infants. [J Perinat Med. 1985]

Comparative
newborn anthropometric data in symmetric versus asymmetric intrauterine
growth retardation. [Am J Obstet Gynecol.
1980]

ReviewThe significance of intrauterine growth restriction
is different from prematurity for the outcome of infants with
gastroschisis. [J
Pediatr Surg. 2004]

Review[Limit of antenatal management of intrauterine
growth retarded fetus] [Nippon Sanka
Fujinka Gakkai Zasshi. 1993]

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