Reference : L'insuffisance mitrale par degenerescence myxoide: aspect biochimique et consideratio...
Scientific journals : Article
Human health sciences : Surgery
http://hdl.handle.net/2268/20650
L'insuffisance mitrale par degenerescence myxoide: aspect biochimique et considerations physiopathologiques.
French
[en] Myxomatous mitral valve degeneration: biochemical aspects and physiopathological considerations
Radermecker, Marc mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie cardio-vasculaire >]
Boulanger, Kevin [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Hulin, Alexia mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Laboratoire des tissus conjonctifs >]
Lambert, Charles mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Laboratoire des tissus conjonctifs >]
Limet, Raymond mailto [Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques >]
Lapière, Charles [> > > >]
Nusgens, Betty mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
2008
Revue Médicale de Liège
Hopital de Baviere
63
4
187-92
Yes (verified by ORBi)
National
0370-629X
2566-1566
Liège
Belgium
[en] Heart Valve Diseases/physiopathology ; Humans ; Mitral Valve/chemistry/pathology ; Mitral Valve Insufficiency/physiopathology
[en] Mitral valve is a complex structure which is submitted to repeated mechanical constraints. In clinical practice, an increasing incidence of mitral insufficiency resulting from myxomatous degeneration is observed. Since myxomatous degeneration is also observed in defined genetic diseases of connective tissues, we propose the hypothesis that idiopathic mitral insufficiency might result from a minor alteration of the interstitial valvular cells and/or their interactions with their support. After a brief review of the role of the extracellular matrix in the heart, some histopathological and biochemical aspects of myxomatous degeneration are presented. Our data and those of the literature will be summarized and a physiopathological hypothesis proposed for myxomatous mitral valve degeneration.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/20650
also: http://hdl.handle.net/2268/17757
contact: <cardiovasc@chu.ulg.ac.be>

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