Horne, J., Beckers, P., Kemik, K., De Bleye, C., Hubert, P., Ziemons, E., & Hubert, C. (31 January 2024). METALLIC NANOPARTICLES CHARACTERIZATION BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY [Poster presentation]. CIRMday 2024, Liege, Belgium. |
Zhang, Y., Houari, S., Van Laethem, T., Dispas, A., Hubert, P., & Hubert, C. (31 January 2024). Development and validation of an LC-MS/MS method for screening and quantification of trace N-nitrosamines in a pharmaceutical formulation [Paper presentation]. CIRM-day. |
Kumari, P., Van Laethem, T., Duroux, D., Fillet, M., Hubert, P., Sacre, P.-Y., & Hubert, C. (04 September 2023). A multi-target QSRR approach to model retention times of small molecules in RPLC. Journal of Pharmaceutical and Biomedical Analysis, 236, 115690. doi:10.1016/j.jpba.2023.115690 |
Zhang, Y., Van Laethem, T., Ziémons Thibault, Dispas, A., Hubert, P., & Hubert, C. (2023). Détermination de nitrosamines dans une matrice médicamenteuse par LC-MS/MS : préparation d’échantillon et défis analytiques. |
Horne, J., De Bleye, C., Lebrun, P., Kemik, K., Van Laethem, T., Sacre, P.-Y., Hubert, P., Hubert, C.* , & Ziemons, E.*. (2023). Optimization of silver nanoparticles synthesis by chemical reduction to enhance SERS quantitative performances: early characterization using the quality by design approach. Journal of Pharmaceutical and Biomedical Analysis, 115475. doi:10.1016/j.jpba.2023.115475 * These authors have contributed equally to this work. |
Oury, C., Meyers, S., Jacques, N., Leeten, K., Jiang, Z., MUSUMECI, L., Lox, M., Debuisson, M., Goffin, E., Pirotte, B., Delvenne, P., Nchimi Longang, A., Hubert, C., Heptia, M., Hubert, P., Kuijpers, M. J. E., Vanassche, T., Martinod, K., Verhamme, P., & Lancellotti, P. (2023). Protective Effect of Ticagrelor Against Infective Endocarditis Induced by Virulent Staphylococcus aureus in Mice. JACC: Basic to Translational Science. doi:10.1016/j.jacbts.2023.02.003 |
Zhang, Y., Thibault, Z., Van Laethem, T., Dispas, A., Hubert, C., & Hubert, P. (27 April 2023). In-silico-assisted development of LC-MS/MS methods for the determination of 17 N-nitrosamines in a drug matrix [Paper presentation]. 21st FORUM OF PHARMACEUTICAL SCIENCES. |
Zhang, Y., Van Laethem, T., Ziémons, T., Dispas, A., Hubert, P., & Hubert, C. (28 March 2023). Développement assisté in silico d’une méthode LC-MS/MS pour la détermination de 17 nitrosamines dans une matrice médicamenteuse [Paper presentation]. 15ème Congrès de l'Association Francophone des Sciences Séparatives (SEP23), Paris, France. |
Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (10 February 2023). Quantitative Structure Retention-Relationship Modeling: Towards an Innovative General-Purpose Strategy. Molecules, 28 (4), 1696. doi:10.3390/molecules28041696 |
Horne, J., Beckers, P., Sacre, P.-Y., De Bleye, C., Hubert, P., Hubert, C., & Ziemons, E. (01 February 2023). Quality by design strategy applied to the synthesis of silver nanoparticles by microwave irradiation [Poster presentation]. CIRMday, liege, Belgium. |
Priyanka Kumari, Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (01 February 2023). A multi-target QSRR(mT-QSRR) approach to model retention time of small pharmaceutical compounds in RPLC [Paper presentation]. CIRM DAY 2023, Liege, Belgium. |
Zhang, Y., Ziémons, T., Van Laethem, T., Dispas, A., Hubert, P., & Hubert, C. (01 February 2023). In-silico-assisted development of LC-MS/MS methods for the determination of 17 N-nitrosamines in a drug matrix [Paper presentation]. CIRM-day. |
Van Laethem, T., Kumari, P., Boulanger, B., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (28 November 2022). User-Driven Strategy for In Silico Screening of Reversed-Phase Liquid Chromatography Conditions for Known Pharmaceutical-Related Small Molecules. Molecules, 27 (23), 8306. doi:10.3390/molecules27238306 |
Zhang, Y., Hubert, P., & Hubert, C. (2022). Investigation of potential substandard dry powder inhalers on EU and North African markets – Evaluation of the delivered and fine particle doses. Journal of Drug Assessment, 1-19. doi:10.1080/21556660.2022.2125727 |
Horne, J., De Bleye, C., Lebrun, P., Sacre, P.-Y., Laurent, A., Kemik, K., Hubert, P., Hubert, C., & Ziemons, E. (13 September 2022). Elaboration of a screening design for the optimization of silver nanoparticles synthesized by chemical reduction based on a Quality by Design approach [Paper presentation]. DA-PBA, Mons, Belgium. |
Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (04 July 2022). QSRR for small pharmaceutical compounds in RPLC: A Machine learning approach [Paper presentation]. 18th Chemometrics in Analytical Chemistry Conference, Rome, Italy. |
Van Laethem, T., Kumari, P., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (June 2022). A pharmaceutical-related molecules dataset for reversed-phase chromatography retention time prediction built on combining pH and gradient time conditions. Data in Brief, 42, 108017. doi:10.1016/j.dib.2022.108017 |
Horne, J., De Bleye, C., Lebrun, P., Sacre, P.-Y., Laurent, A., Kemik, K., Hubert, C., Hubert, P., & Ziemons, E. (20 May 2022). Optimisation robuste de la synthèse de nanoparticules d’argent en vue de leur utilisation en spectroscopie Raman exaltée de surface [Paper presentation]. GFSV 2022, Nivelles, Belgium. |
Van Laethem, T., Kumari, P., Fillet, M., Hubert, P., Hubert, C., & Sacre, P.-Y. (18 May 2022). In-silico screening for the development of robust reversed-phase liquid chromatography methods of known small molecules based on QSRR and desirability index [Paper presentation]. 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-17), Gent, Belgium. |
Horne, J., De Bleye, C., Laurent, A., Kemik, K., Hubert, C., Hubert, P., & Ziemons, E. (02 February 2022). Combining characterization tools for screening of critical parameters leading to reproducible synthesis of silver nanoparticles [Paper presentation]. CIRMday 2022, Liege, Belgium. |
Van Laethem, T., Kumari, P., Fillet, M., Hubert, P., Hubert, C., & Sacre, P.-Y. (02 February 2022). Elaboration of a strategy for in silico screening for reversed-phase liquid chromatography method development [Paper presentation]. CIRM-day 2022, Liège, Belgium. |
Jambo, H., Dispas, A., Hubert, C., Lecomte, F., Ziemons, E., & Hubert, P. (2022). Generic SFC-MS methodology for the quality control of vitamin D3 oily formulations. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2021.114492 |
Kemik, K., Horne, J., De Bleye, C., Ziemons, E., Hubert, P., & Hubert, C. (2022). Characterization of silver nanoparticles by inductively coupled plasma mass spectrometry [Paper presentation]. CIRMday 2022, Liège, Belgium. |
Dispas, A., Hubert, C., & Hubert, P. (December 2021). Perspective: What constitutes a quality paper in drug analysis? Talanta Open, 4, 100054. doi:10.1016/j.talo.2021.100054 |
Van Laethem, T., Kumari, P., Fillet, M., Hubert, P., Hubert, C., & Sacre, P.-Y. (05 October 2021). Modélisation du temps de rétention de petites molécules pharmaceutiques en chromatographie liquide en phase inverse basée sur le QSRR et les surfaces de réponse [Poster presentation]. 14ème Congrès Francophone sur les Sciences Séparatives et les Couplages de l'AFSEP, Paris, France. |
Deidda, R., Avohou, T. H., Dumont, E., Hubert, C., Hubert, P., De Bleye, C., & Ziemons, E. (2021). Application of the analytical quality by design principles to the development of a qualitative surface-enhanced Raman scattering method: A proof of concept. Journal of Raman Spectroscopy. doi:10.1002/jrs.6249 |
Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (22 July 2021). A QSRR modelling of small pharmaceutical compounds in Reverse Phase Liquid Chromatography [Paper presentation]. MLSS 2021 TAIPEI (Machine Learning Summer School), TAIPEI, Taiwan. |
Van Laethem, T., Kumari, P., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (24 May 2021). Adaptive response surface model of small pharmaceutical compounds in reverse phase liquid chromatography [Paper presentation]. CIRM-day 2021, Liège, Belgium. |
Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (03 February 2021). Quantitative structure-retention relationship modelling of small pharmaceutical compounds in reverse phase liquid chromatography [Paper presentation]. e-CHIMIOMETRIE 2021. |
Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (03 February 2021). Quantitative structure-retention relationship modelling of small pharmaceutical compounds in reverse phase liquid chromatography [Paper presentation]. Chimiométrie. |
Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (2021). QSRR modelling of small pharmaceutical compounds in Liquid Chromatography [Paper presentation]. Summer Research internship, Milan, Italy. |
Lecomte, F.* , Aerts, J.* , Plenevaux, A., Defraiteur, C., Chappuis-Hugon, F., Rozet, E., CHIAP, P., Luxen, A., Pichon, V., Hubert, P.* , & Hubert, C.*. (20 February 2020). Performance evaluation of a MIP for the MISPE-LC determination of p-[18F]MPPF and a potential metabolite in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 180. doi:10.1016/j.jpba.2019.113015 * These authors have contributed equally to this work. |
Hubert, C., Deidda, R., Dispas, A., Van Laethem, T., Zhao, X., Lebrun, P., & Hubert, P. (28 January 2020). Implementing principles of Analytical Quality by Design (AQbD) for method development in quality control environment [Paper presentation]. 16th International Symposium on Hyphenated Techniques in Chromatography and Separation technology, Ghent, Belgium. |
Deidda, R., Avohou, T. H., Jambo, H., Dispas, A., Orlandini, S., Hubert, P., Ziemons, E., & Hubert, C. (20 May 2019). Principles of Analytical Quality by Design for the development of quality control methods in a pharmaceutical context [Paper presentation]. 20th Forum of Pharmaceutical Sciences - BSPS, Brussels, Belgium. |
Deidda, R., Mignolet, M., Jambo, H., Dispas, A., Hubert, P., & Hubert, C. (26 March 2019). Développement d’une méthode SFC-MS pour le dosage de vitamines en matrice complexe : Application de la stratégie « Analytical Quality by Design » [Paper presentation]. 13ème Congrès Francophone sur les sciences séparatives et les couplages (SEP2019), Paris, France. |
Hubert, C., Widart, J., Ziemons, E., & Hubert, P. (2019). Process Analysis: Maintenance, Reliability, and Training. In Encyclopedia of Analytical Science 3rd Edition. Elsevier. doi:10.1016/B978-0-12-409547-2.14530-5 |
Ziemons, E., Hubert, C., & Hubert, P. (2019). Process Analysis - Overview. In M. Miro, P. Worsfold (Ed.), A. Townshend (Ed.), ... C. Poole (Ed.), Encyclopedia of Analytical Science (3rd Edition, pp. 1-7). Amsterdam, Netherlands: Elsevier. doi:10.1016/B978-0-12-409547-2.14051-X |
Deidda, R., Avohou, T. H., Kasemiire, A., Dumont, E., De Bleye, C., Hubert, P., Hubert, C., & Ziemons, E. (30 January 2019). Optimisation of a surface enhanced Raman scattering method using design of experiments and Bayesian design space modelling [Poster presentation]. Chimiométrie XIX - 2019, Montpellier, France. |
Deidda, R., Avohou, T. H., Baronti, R., Davolio, P. L., Pasquini, B., Del Bubba, M., Hubert, C., Hubert, P., Orlandini, S., & Furlanetto, S. (2019). Analytical quality by design: development and control strategy for a LC method to evaluate the cannabinoids content in cannabis olive oil extracts. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2019.01.032 |
Deidda, R., Avohou, T. H., Orlandini, S., Baronti, R., Pasquini, B., Furlanetto, S., Hubert, P., & Hubert, C. (19 December 2018). Control strategy applied to a LC-DAD quality control method as part of the analytical quality by design approach: one year of routine use [Paper presentation]. 1st CIRM Scientific Day, Liège, Belgium. |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (19 December 2018). SFC-MS for the quality control of cannabis: addressing the potential adulteration with synthetic cannabinoids [Paper presentation]. CIRM Day (1st edition). |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (19 October 2018). SFC-MS as a preventive tool for the quality control of potentially adulterated cannabis with synthetic cannabinoids [Paper presentation]. SFC 2018, Strasbourg, France. |
Deidda, R., Avohou, T. H., Orlandini, S., Baronti, R., Pasquini, B., Furlanetto, S., Hubert, P., & Hubert, C. (September 2018). Analytical Quality by Design: development and control strategy for a RP-HPLC method implemented in routine to evaluate the cannabinoids content in cannabis olive oil extracts [Poster presentation]. International Symposium DA-BPA 2018, Leuven, Belgium. |
Deidda, R., Orlandini, S., Hubert, P., & Hubert, C. (July 2018). Risk-based approach for method development in pharmaceutical quality control context: A critical review. Journal of Pharmaceutical and Biomedical Analysis, 161, 110-121. doi:10.1016/j.jpba.2018.07.050 |
Jambo, H., Hubert, C., & Hubert, P. (21 June 2018). Comment garantir la fiabilité de vos futurs résultats ? [Paper presentation]. CCVS Validation de méthodes, Rouen, France. |
Dispas, A., Avohou, T. H., Lebrun, P., Hubert, P., & Hubert, C. (April 2018). ‘Quality by Design’ approach for the analysis of impurities in pharmaceutical drug products and drug substances. TrAC: Trends in Analytical Chemistry, 101, 24-33. doi:10.1016/j.trac.2017.10.028 |
Avohou, T. H., Hubert, C., Debrus, B., Lebrun, P., Rudaz, S., Boulanger, B., & Hubert, P. (2018). Statistical methods in Quality by Design approach to Liquid Chromatography method development. In S. Fekete & I. Molnar, Software-Assisted Method Development for Modeling High Performance Liquid Chromatography (pp. 109-150). London, United Kingdom: World Scientific Publishing. doi:10.1142/q0161 |
De Bleye, C., Dumont, E., Hubert, C., Jambo, H., Lejeune, R., Ziemons, E., & Hubert, P. (2018). Travaux Pratiques: Introduction à la Chimie Analytique Pharmaceutique_Présentation. |
De Bleye, C., Dumont, E., Hubert, C., Jambo, H., Lejeune, R., Ziemons, E., & Hubert, P. (2018). Pré-requis aux travaux pratiques de chimie analytique - Deuxième baccalauréat en Sciences pharmaceutiques. (ULiège - Université de Liège, Belgium, CHIM0321-3 Travaux pratiques - Introduction à la chimie analytique). |
De Bleye, C., Dumont, E., Hubert, C., Jambo, H., Lejeune, R., Ziemons, E., & Hubert, P. (2018). Notes des travaux pratiques de chimie analytique - Deuxième baccalauréat en Sciences pharmaceutiques. (ULiège - Université de Liège, Belgium, CHIM0321-3 Travaux pratiques - Introduction à la chimie analytique). |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (2018). Quality control of medicinal cannabis: implementation of a generic sfc-ms method to address counterfeiting with synthetic cannabinoids [Poster presentation]. International Symposium DA-PBA 2018, Leuven, Belgium. |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (2018). Implementation of a generic SFC-MS method for the quality control of potentially counterfeited medicinal cannabis with synthetic cannabinoids. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1092, 332-342. doi:10.1016/j.jchromb.2018.05.049 |
Hubert, C., Lebrun, P., Boulanger, B., & Hubert, P. (23 November 2017). Intégration de la validation dans le concept AQbD [Paper presentation]. AFSEP - "La validation dans l'incertitude, l'incertitude dans la validation : comment garder le sourire?", Paris, France. |
Hubert, C., Lebrun, P., Boulanger, B., & Hubert, P. (11 May 2017). Cycle de vie des méthodes, vers une maîtrise intégrée des performances quantitatives [Paper presentation]. AFSEP - Comment garantir un résultat quantitatif ?, Lyon, France. |
Hubert, C., Houari, S., Lebrun, P., Rozet, E., & Hubert, P. (28 March 2017). Validation de l'espace opérationnel : de l'optimisation à la validation en une seule étape [Poster presentation]. 12ème Congrès de l'Association Francophone des Sciences Séparatives, Paris, France. |
De Bleye, C., Dumont, E., Dispas, A., Hubert, C., Sacre, P.-Y., Netchacovitch, L., De Muyt, B., Kevers, C., Dommes, J., Hubert, P., & Ziemons, E. (August 2016). Monitoring of anatabine release by methyl jasmonate elicited BY-2 cells using surface-enhanced Raman scattering. Talanta, 160, 754-760. doi:10.1016/j.talanta.2016.08.027 |
Netchacovitch, L., Thiry, J., De Bleye, C., Dumont, E., Dispas, A., Hubert, C., Krier, F., Sacre, P.-Y., Evrard, B., Hubert, P., & Ziemons, E. (July 2016). A simple calibration approach based on film-casting for confocal Raman microscopy to support the development of a Hot-Melt Extrusion process. Talanta, 154, 392-399. doi:10.1016/j.talanta.2016.03.080 |
De Bleye, C., Dumont, E., Dispas, A., Hubert, C., Sacre, P.-Y., Netchacovitch, L., De Muyt, B., Kevers, C., Dommes, J., Hubert, P., & Ziemons, E. (19 May 2016). Use of SERS to monitor the anatabine release in the culture medium by methyl jasmonate elicited BY-2 cells [Poster presentation]. Raman Fest 2016, Berlin, Germany. |
Hubert, C., Lebrun, P., Rozet, E., & Hubert, P. (10 May 2016). Implementing principles of Quality by Design (QbD) in validation context [Paper presentation]. Eurachem International Workshop - Method Validation in Analytical Science - Current Practices and Future Challenges, Ghent, Belgium. |
Hubert, C. (2015). Gestion du risque associé au cycle de vie des méthodes analytiques : Applications aux molécules de faibles poids moléculaires analysées par Spectrométrie de Masse [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/186348 |
De Bleye, C., Dumont, E., Hubert, C., Sacre, P.-Y., Netchacovitch, L., Chavez, P.-F., Hubert, P., & Ziemons, E. (August 2015). A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering. Analytica Chimica Acta, 888, 118-125. doi:10.1016/j.aca.2015.07.023 |
Ziemons, E., Hubert, C., Marini Djang'Eing'A, R., Rozet, E., Lebrun, P., Boulanger, B., & Hubert, P. (12 May 2015). Validation des méthodes analytiques: Approche basée sur l'erreur totale [Paper presentation]. Chimie Analytique et chimie des eaux, Mons, Belgium. |
Rozet, E., Debrus, B., Lebrun, P., Boulanger, B., Hubert, C., & Hubert, P. (22 January 2015). Design Space for Analytical Methods: Why ? What ? How ? [Paper presentation]. AFSEP - Innovation en développements de méthodes, Lyon, France. |
Hubert, C., Houari, S., Rozet, E., Lebrun, P., & Hubert, P. (2015). Towards a full integration of optimization and validation phases: An Analytical-Quality-by-Design approach. Journal of Chromatography. A. doi:10.1016/j.chroma.2015.03.059 |
Hubert, C., Lebrun, P., Houari, S., Ziemons, E., Rozet, E., & Hubert, P. (25 January 2014). Improvement of a stability-indicating method by Quality-by-Design versus Quality-by-Testing: A case of a learning process. Journal of Pharmaceutical and Biomedical Analysis, 88, 401-409. doi:10.1016/j.jpba.2013.09.026 |
Hubert, C., Lebrun, P., Houari, S., Dispas, A., Rozet, E., Ziemons, E., & Hubert, P. (July 2013). Innovative strategy based on the quality by design concept for the development of a LC/MS method [Poster presentation]. 24th Symposium on Pharmaceutical and Biomedical Analysis, Bologna, Italy. |
Hubert, C., Lebrun, P., Houari, S., Dispas, A., Rozet, E., Ziemons, E., & Hubert, P. (June 2013). Innovative strategy based on the quality by design concept for the development of a LC/MS method [Poster presentation]. 10ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Paris, France. |
Hubert, C., Lebrun, P., Houari, S., Bakima, P., Rozet, E., Ziemons, E., & Hubert, P. (20 June 2012). First Application of an Innovative Design Space Optimization Strategy for the Development of a LC/MS Method [Poster presentation]. 38th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Anaheim, United States - California. |
Dispas, A., Lebrun, P., Hubert, C., Thiébaut, D., Vial, J., & Hubert, P. (June 2012). INNOVATIVE GREEN SUPERCRITICAL FLUID CHROMATOGRAPHY DEVELOPMENT FOR THE SEPARATION OF NEUROTRANSMITTERS USING DESIGN SPACE STRATEGY [Poster presentation]. HPLC 2012, Anaheim, California, United States. |
Mbinze Kindenge, J., Lebrun, P., Debrus, B., Dispas, A., Hubert, C., Rozet, E., Marini Djang'Eing'A, R., & Hubert, P. (June 2012). APPLICATION OF AN INNOVATIVE DESIGN SPACE OPTIMIZATION STRATEGY TO THE DEVELOPMENT OF LC METHODS TO COMBAT POTENTIALLY COUNTERFEIT NSAIDS [Poster presentation]. HPLC 2012, Anaheim, California, United States. |
Lecomte, F., Hubert, C., Demarche, S., De Bleye, C., Dispas, A., Jost, M., Frankenne, F., Ceccato, A., Rozet, E., & Hubert, P. (05 January 2012). Comparison of the quantitative performances and measurement uncertainty estimates obtained during method validation versus routine applications of a novel hydrophilic interaction chromatography method for the determination of cidofovir in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 57, 153-165. doi:10.1016/j.jpba.2011.08.040 |
Bouabidi, A., Ziemons, E., Marini Djang'Eing'A, R., Hubert, C., Talbi, M., Bourichi, H., El Karbane, M., Boulanger, B., Hubert, P., & Rozet, E. (2012). Usefulness of capability indices in the framework of analytical methods validation. Analytica Chimica Acta, 714, 47-56. doi:10.1016/j.aca.2011.11.019 |
Hubert, C., Ziemons, E., & Hubert, P. (2011). LCA-GE-005- Rapport de validation - VR001_V01. |
Hubert, C., Streel, B., Sibenaler, R., Widart, J., Ceccato, A., & Hubert, P. (19 June 2011). High Throughput determination of Levonorgestrel in human plasma using a Sensitive LC-MS/MS method [Poster presentation]. 36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary. |
Hubert, C., Ziemons, E., & Hubert, P. (2011). Protocole d'essai LC/MS - P001 - V01. |
Hubert, C., Ziemons, E., & Hubert, P. (2011). Qualitative analysis of potentials compounds contained in an aged matrix of a pharmaceutical speciality at the RT of an impurity. |
Hubert, C., Ziemons, E., & Hubert, P. (2011). Rapport de validation LC/MS - PVR-001 - V02. |
Hubert, C., Ziemons, E., & Hubert, P. (2011). Comparison between new and old excipients. |
Hubert, C., Ziemons, E., & Hubert, P. (2010). Report of the development of a LC-MS method for the assay of an impurity in a pharmaceutical speciality. |
Lecomte, F., Jasselette, C., Hubert, C., Demarche, S., De Bleye, C., Ceccato, A., Rozet, E., & Hubert, P. (September 2010). Validation of a HILIC method for the determination of cidofovir in plasma [Poster presentation]. Drug Analysis 2010 - International Symposium on Drug Analysis, Antwerp, Belgium. |
Marini Djang'Eing'A, R., Lambert, V., Denooz, R., Charlier, C., Hubert, C., Hubert, P., & Rozet, E. (September 2010). TOLERANCE INTERVALS AS CONTROL CHART: COMPARISON TO CLASSIC SHEWHART X̅-R CONTROL CHART [Poster presentation]. International Symposium on Drug Analysis 2010, Anvers, Belgium. |
Marini Djang'Eing'A, R., Rozet, E., Hubert, C., Ziemons, E., & Hubert, P. (March 2010). Estimation of uncertainty from the total error strategy: Application to internal and normative methods. Acta Clinica Belgica, 65, 100-104. |
Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (26 January 2010). Développement et validation d'une méthode de dosage de la glucosamine par SPE/LC/MS dans le plamsa canin [Paper presentation]. Forum des jeunes chercheurs du C.I.R.M, Liège, Belgium. |
Lecomte, F., Hubert, C., Rozet, E., & Hubert, P. (26 January 2010). Intérêt de la chromatographie en mode HILIC pour le dosage du cidofovir dans des fluides biologiques [Paper presentation]. Forum des jeunes chercheurs du CIRM - 26 janvier 2010 - ULg, Liège, Belgium. |
Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (2010). Development and validation of a sensitive solid phase extraction/hydrophilic interaction liquid chromatography/mass spectrometry method for the accurate determination of glucosamine in dog plasma. Journal of Chromatography. A, 1217, 3275-3281. doi:10.1016/j.chroma.2010.01.024 |
Hubert, C., Ziemons, E., Rozet, E., Breuer, A., Lambert, A., Jasselette, C., De Bleye, C., Lejeune, R., & Hubert, P. (January 2010). Development and validation of a quantitative method for the selective determination of tin species in tin octoate by differential pulse polarography. Talanta, 80 (3), 1413-1420. doi:10.1016/j.talanta.2009.09.045 |
Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (01 December 2009). Développement et validation d'une méthode de dosage de la glucosamine par SPE/HILIC/MS dans le plamsa de chien [Poster presentation]. 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Marseille, France. |
Lecomte, F., Demarche, S., Evrard, S., Delaunay, S., Hubert, C., Rozet, E., & Hubert, P. (01 December 2009). Intérêt de la chromatographie liquide d'interactions hydrophiles pour l'analyse de composés polaires dans des matrices complexes [Paper presentation]. 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP09, Marseille, France. |
Hubert, C., Ziemons, E., & Hubert, P. (2009). Rapport final de développement et de validation de l'étain dans l'octanoate d'étain. |
Marini Djang'Eing'A, R., Rozet, E., Hubert, C., Ziemons, E., & Hubert, P. (October 2009). Estimation de l’incertitude à partir de la stratégie de l’erreur totale : Application pour des méthodes internes et des méthodes normatives [Poster presentation]. 4ème journées internationales de Toxicologie, Liège, Belgium. |
Hubert, C., Houari, S., Houbart, V., De Bleye, C., Fillet, M., Rozet, E., & Hubert, P. (June 2009). Development and validation of a sensitive SPE/LC/MS method for the determination of glucosamine in dog plasma [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Dresden, Germany. |
Hubert, C., Ziemons, E., & Hubert, P. (2009). Développement et validation d'une méthode de dosage de la glucosamine dans le plasma cannin par SPE/LC/MS. |
Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Hubert, C., Moonen, F., & Hubert, P. (2008). Simultaneous improvement of the predictive character of the validation data and estimation of measurement uncertainty [Paper presentation]. Agrostat, Louvain-la-Neuve, Belgium. |
Dalmi, M., Hubert, C., Breuer, A., & Hubert, P. (November 2007). Spéciation et dosage de Sn(IV) dans un catalyseur, l'octanoate d'étain (II). Etude de deux paramètres importants du processus analytique [Poster presentation]. JSNES 2007, Mohammedia, Morocco. |
Rozet, E., Hubert, C., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (27 July 2007). Using tolerance intervals in pre-study validation of analytical methods to predict in-study results - The fit-for-future-purpose concept. Journal of Chromatography. A, 1158 (1-2), 126-137. doi:10.1016/j.chroma.2007.03.102 |
Hubert, C., streel, B., Sibenaler, R., Chiap, P., & Hubert, P. (July 2007). Development and pre-validation of a high sensitive method for the determination of levonorgestrel in human plasma by SPE/LC/MS-MS [Poster presentation]. 31th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Gand, Belgium. |
Hubert, C., Rozet, E., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (March 2007). Validation versus routine : Evaluation de l'aspect prédictif de l'intervalle de tolérance [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Grenoble, France. |
Rozet, E., Ceccato, A., Hubert, C., Ziemons, E., Oprean, R., Rudaz, S., Boulanger, B., & Hubert, P. (2007). Analysis of recent pharmaceutical regulatory documents on analytical method validation. Journal of Chromatography. A, 1158 (1-2), 111-25. doi:10.1016/j.chroma.2007.03.111 |
Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Hubert, C., Marini Djang'Eing'A, R., Moonen, F., & Hubert, P. (2007). PREDICTION OF THE RISKS LINKED TO THE DATA GENERATED DURING THE LIFE CYCLE OF QUANTITATIVE ANALYTICAL METHODS [Paper presentation]. 13eme Forum des Sciences Pharmaceutiques, Spa, Belgium. |
Hubert, C., Ziemons, E., & Hubert, P. (2006). Val06-004 - Validation du dosage du LNG contenu dans les réservoirs du Levosert-20. |
Hubert, C. (2006). Optimisation et validation de deux méthodes de dosage dans le cadre de la mise au point d'un dispositif intra-utérin à libération hormonale contrôlée [Specialised master, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/39304 |
Hubert, C., Lambert, A., Ziemons, E., Hubert, P., & Lejeune, R. (May 2006). Speciation analysis of Sn(II) and Sn(IV) in stannous octoate using differential pulse polarography [Poster presentation]. Drug Analysis 2006, Namur, Belgium. |
Hubert, C., Rozet, E., Boulanger, B., Dewé, W., Breuer, A., Collard, L., Evrard, B., & Hubert, P. (May 2006). Validation of a LC method for the determination of levonorgestrel released from a polymeric matrix. A two days protocol [Poster presentation]. Drug Analysis 2006, Namur, Belgium. |
Hubert, C. (2004). Préparation d'un dépôt en couche mince du supraconducteur Y-123 par la technique sol-gel [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/147348 |
Henrist, C., Traina, K., Hubert, C., Toussaint, G., Rulmont, A., & Cloots, R. (June 2003). Study of the morphology of copper hydroxynitrate nanoplatelets obtained by controlled double jet precipitation and urea hydrolysis. Journal of Crystal Growth, 254 (1-2), 176-187. doi:10.1016/S0022-0248(03)01145-X |